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2型糖尿病患者的QRS和QT间期改变

QRS and QT Interval Modifications in Patients with Type 2 Diabetes Mellitus.

作者信息

Chávez-González Elibet, Calero Yuliet María Echavarría, Harrichand Suruj, Mensah Edward Bediako

机构信息

Electrophysiology department, Cardiocentro Ernesto Guevara, Santa Clara, Cuba.

Cardiology Service, Celestino Hernandez Robau Hospital.

出版信息

Curr Health Sci J. 2022 Jul-Sep;48(3):270-276. doi: 10.12865/CHSJ.48.03.04. Epub 2022 Sep 30.

DOI:10.12865/CHSJ.48.03.04
PMID:36815079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9940933/
Abstract

INTRODUCTION

Diabetes Mellitus imbricates inflammatory processes on their pathophysiology, it could affect cardiac electrophysiology. Cardiac inflammatory process leads electrocardiogram changes. Nevertheless, there are discrepancies about whether it prolongs or decreases waves and intervals such as QRS and QT. Furthermore, QRS dispersion has not been studied.

OBJECTIVE

To identify QRS complex and QT interval modifications in type 2 diabetic patients.

METHODS

A descriptive cross-sectional study was carried out in 59 type 2 diabetic patients selected by non-probabilistic sampling. Electrocardiogram was performed, QRS and QT interval were measured manually by two observers. Dispersion of both variables was calculated to compare with normal values.

RESULTS

Two variables showed differences for sex, QRS dispersion was higher in females (45.84), p=0.0001 vs. reference value; QT dispersion (63.12) showed significance difference (p=0.0246) vs. reference value for males. Greater than five years of illness was related to higher QRS values (124.11 vs. 137.28), p=0.005 and corrected QT dispersion (61.81 vs. 78.79), p=0.022.

CONCLUSIONS

The electrocardiographic differences between sexes may suggest a gender influence. The longer duration of diabetes diseases could increase cardiovascular risk of arrhythmias due to greater QRS duration and corrected QT interval prolongation.

摘要

引言

糖尿病在其病理生理学中涉及炎症过程,可能影响心脏电生理学。心脏炎症过程会导致心电图改变。然而,关于它是延长还是缩短诸如QRS和QT等波和间期,存在差异。此外,尚未对QRS离散度进行研究。

目的

确定2型糖尿病患者的QRS波群和QT间期改变。

方法

对通过非概率抽样选取的59例2型糖尿病患者进行描述性横断面研究。进行心电图检查,由两名观察者手动测量QRS和QT间期。计算两个变量的离散度并与正常值进行比较。

结果

两个变量在性别上存在差异,女性的QRS离散度更高(45.84),p = 0.0001,与参考值相比;男性的QT离散度(63.12)与参考值相比有显著差异(p = 0.0246)。患病超过五年与更高的QRS值相关(124.11对137.28),p = 0.005,以及校正后的QT离散度(61.81对78.79),p = 0.022。

结论

性别之间的心电图差异可能表明存在性别影响。糖尿病病程较长可能会因QRS时限延长和校正后的QT间期延长而增加心律失常的心血管风险。

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本文引用的文献

1
Ventricular arrhythmias are associated with increased QT interval and QRS dispersion in patients with ST-elevation myocardial infarction.在ST段抬高型心肌梗死患者中,室性心律失常与QT间期延长和QRS波离散度增加有关。
Rev Port Cardiol. 2022 May;41(5):395-404. doi: 10.1016/j.repc.2021.03.015. Epub 2022 Mar 9.
2
U300 Insulin Glargine: A Novel Basal Insulin for Type 1 and Type 2 Diabetes.U300甘精胰岛素:一种用于1型和2型糖尿病的新型基础胰岛素。
J Pharm Technol. 2015 Oct;31(5):234-242. doi: 10.1177/8755122515584193. Epub 2015 Apr 29.
3
Prevalence of ECG abnormalities in people with type 2 diabetes: The Hoorn Diabetes Care System cohort.2 型糖尿病患者心电图异常的患病率:Hoorn 糖尿病护理系统队列研究。
J Diabetes Complications. 2021 Feb;35(2):107810. doi: 10.1016/j.jdiacomp.2020.107810. Epub 2020 Nov 26.
4
Normal limits of the electrocardiogram in Angolans.安哥拉人心电图的正常范围。
J Electrocardiol. 2020 Nov-Dec;63:68-74. doi: 10.1016/j.jelectrocard.2020.10.011. Epub 2020 Oct 26.
5
[Gender differences in the mortality of people with type 2 diabetes: Asturias Study 2018].
Gac Sanit. 2020 Sep-Oct;34(5):442-448. doi: 10.1016/j.gaceta.2019.02.014. Epub 2019 Apr 24.
6
Evaluation of ECG Abnormalities in Patients with Asymptomatic Type 2 Diabetes Mellitus.无症状2型糖尿病患者心电图异常的评估
J Clin Diagn Res. 2017 Apr;11(4):OC39-OC41. doi: 10.7860/JCDR/2017/24882.9740. Epub 2017 Apr 1.
7
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8
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