Amsterdam UMC, Vrije Universiteit Amsterdam, Department of General Practice Medicine, Amsterdam Public Health Research Institute, De Boelelaan 1117, Amsterdam, the Netherlands.
Amsterdam UMC, Vrije Universiteit Amsterdam, Department of General Practice Medicine, Amsterdam Public Health Research Institute, De Boelelaan 1117, Amsterdam, the Netherlands.
J Diabetes Complications. 2021 Feb;35(2):107810. doi: 10.1016/j.jdiacomp.2020.107810. Epub 2020 Nov 26.
The American Diabetes Association, and the joint European Society of Cardiology and European Association for the Study of Diabetes guidelines recommend a resting ECG in people with type 2 diabetes with hypertension or suspected cardiovascular disease (CVD). However, knowledge on the prevalence of ECG abnormalities is incomplete. We aimed to analyse the prevalence of ECG abnormalities and their cross-sectional associations with cardiovascular risk factors in people with type 2 diabetes.
We used data of the Diabetes Care System cohort obtained in 2018. ECG abnormalities were defined using the Minnesota Classification and categorised into types of abnormalities. The prevalence was calculated for the total population (n = 8068) and the subgroup of people without a history of CVD (n = 6494). Logistic regression models were used to asses cross-sectional associations.
Approximately one-third of the total population had minor (16.0%) or major (13.1%) ECG abnormalities. Of the participants without a CVD history, approximately one-quarter had minor (14.9%) or major (9.1%) ECG abnormalities, and for those with hypertension or very high CVD risk, the prevalence was 27.5% and 39.6%, respectively. ECG abnormalities were significantly and consistently associated with established CVD risk factors.
Resting ECG abnormalities are common in all people with type 2 diabetes (29.1%), including those without a history of CVD (24.0%), and their prevalence is related to traditional cardiovascular risk factors such as older age, male sex, hypertension, lower HDL cholesterol, higher BMI, and smoking behaviour.
美国糖尿病协会以及欧洲心脏病学会和欧洲糖尿病研究协会联合指南建议，2 型糖尿病合并高血压或疑似心血管疾病（CVD）的患者应进行静息心电图检查。然而，对于心电图异常的流行程度，我们的了解并不完整。本研究旨在分析 2 型糖尿病患者中心电图异常的流行情况及其与心血管危险因素的横断面相关性。
我们使用了 2018 年获得的糖尿病护理系统队列的数据。使用明尼苏达分类法定义心电图异常，并将其分类为异常类型。我们计算了总人群（n=8068）和无 CVD 病史人群（n=6494）的异常发生率。使用逻辑回归模型评估横断面相关性。
大约三分之一的总人群存在轻微（16.0%）或严重（13.1%）的心电图异常。在无 CVD 病史的参与者中，大约四分之一存在轻微（14.9%）或严重（9.1%）的心电图异常，而对于高血压或极高 CVD 风险的患者，其发生率分别为 27.5%和 39.6%。心电图异常与已确立的 CVD 危险因素显著且一致相关。
静息心电图异常在所有 2 型糖尿病患者中都很常见（29.1%），包括无 CVD 病史的患者（24.0%），其发生率与年龄较大、男性、高血压、较低的高密度脂蛋白胆固醇、较高的 BMI 和吸烟行为等传统心血管危险因素有关。
