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前列腺尿道透明细胞腺癌伴异时性前列腺腺癌

Clear cell adenocarcinoma of the prostatic urethra with metachronous prostate adenocarcinoma.

作者信息

Wang Henry, Ting Francis, Samra Spinder, Mcleod Duncan, Nalavenkata Sunny, Kim Lawrence

机构信息

Urology Department, Westmead Hospital, Westmead, NSW, Australia.

Anatomical Pathology Department, Westmead Hospital, Westmead, NSW, Australia.

出版信息

Urol Case Rep. 2023 Jan 30;47:102338. doi: 10.1016/j.eucr.2023.102338. eCollection 2023 Mar.

DOI:10.1016/j.eucr.2023.102338
PMID:36816610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9932366/
Abstract

A 70-year-old male underwent a Transurethral Resection of Prostate for the management of obstructive voiding symptoms. On cystoscopy, papillary frond-like lesions up to 2cm in size were encountered, overlying the right side of the prostatic urethra. Histopathology from the resection revealed clear cell adenocarcinoma (CCA) of the prostatic urethra. Primary clear cell adenocarcinoma of the prostatic urethra is exceedingly rare, with as few as 9 cases reported. We review the literature for its oncogenesis, discuss the histopathological features for diagnosis and report on our surgical management and outcome.

摘要

一名70岁男性因梗阻性排尿症状接受了经尿道前列腺切除术。膀胱镜检查时,在前列腺尿道右侧发现了大小达2厘米的乳头状叶状病变。切除组织的组织病理学检查显示为前列腺尿道透明细胞腺癌(CCA)。原发性前列腺尿道透明细胞腺癌极为罕见,仅有9例报道。我们回顾了其肿瘤发生的文献,讨论了诊断的组织病理学特征,并报告了我们的手术治疗及结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/95cbaa8f61dd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/82d6e0144fe1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/17072dbbf455/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/95cbaa8f61dd/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/82d6e0144fe1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/17072dbbf455/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4614/9932366/95cbaa8f61dd/gr3.jpg

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Clear cell adenocarcinoma of the prostatic urethra with metachronous prostate adenocarcinoma.前列腺尿道透明细胞腺癌伴异时性前列腺腺癌
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本文引用的文献

1
Clear Cell Adenocarcinoma in Men: A Series of 15 Cases.男性透明细胞腺癌:15例病例系列
Am J Surg Pathol. 2021 Feb 1;45(2):270-276. doi: 10.1097/PAS.0000000000001589.
2
Clear cell adenocarcinoma of the prostatic urethra: A case report.前列腺尿道透明细胞腺癌:一例报告。
IJU Case Rep. 2018 Nov 24;2(1):19-22. doi: 10.1002/iju5.12028. eCollection 2019 Jan.
3
The epidemiology and role of surgery in the treatment of urethral clear cell carcinoma.尿道透明细胞癌的流行病学及手术在其治疗中的作用
Int Urol Nephrol. 2020 Jan;52(1):51-57. doi: 10.1007/s11255-019-02289-w. Epub 2019 Sep 25.
4
Clear cell adenocarcinoma of the urethra: review of the literature.尿道透明细胞腺癌:文献综述
Int J Surg Oncol. 2015;2015:790235. doi: 10.1155/2015/790235. Epub 2015 Jan 20.
5
Primary urethral clear-cell adenocarcinoma: comprehensive analysis by surgical pathology, cytopathology, and next-generation sequencing.原发性尿道透明细胞腺癌:通过外科病理学、细胞病理学和下一代测序进行的综合分析
Am J Pathol. 2014 Mar;184(3):584-91. doi: 10.1016/j.ajpath.2013.11.023. Epub 2014 Jan 3.