Son A Yeon, Chung Hye Won
J Korean Soc Radiol. 2023 Jan;84(1):150-169. doi: 10.3348/jksr.2021.0179. Epub 2022 May 23.
Multiple myeloma (MM) is a malignant hematologic disease caused by the proliferation of clonal plasma cells in the bone marrow, and its incidence is increasing in Korea. With the development of treatments for MM, the need for early diagnosis and treatment has emerged. In recent years, the International Myeloma Working Group (IMWG) has been constantly revising the laboratory and radiological diagnostic criteria for MM. In addition, as whole-body MRI (WBMR) has been increasing used in the diagnosis and treatment response evaluation of patients with MM, the Myeloma Response Assessment and Diagnosis System (MY-RADS) was created to standardize WBMR image acquisition techniques, image interpretation, and response evaluation methods. Radiologists need to have a detailed knowledge of the features of MM for accurate diagnosis. Thus, in this review article, we describe the imaging method for MM according to the latest IMWG guidelines as well as the image acquisition and response evaluation technique for WBMR according to MY-RADS.
多发性骨髓瘤(MM)是一种由骨髓中克隆性浆细胞增殖引起的恶性血液疾病,在韩国其发病率呈上升趋势。随着MM治疗方法的发展,对早期诊断和治疗的需求应运而生。近年来,国际骨髓瘤工作组(IMWG)一直在不断修订MM的实验室和放射学诊断标准。此外,由于全身MRI(WBMR)在MM患者的诊断和治疗反应评估中使用越来越多,因此创建了骨髓瘤反应评估和诊断系统(MY-RADS),以规范WBMR图像采集技术、图像解读和反应评估方法。放射科医生需要详细了解MM的特征才能进行准确诊断。因此,在这篇综述文章中,我们根据IMWG的最新指南描述了MM的成像方法,以及根据MY-RADS的WBMR图像采集和反应评估技术。