Tatar Gamze, Alçın Göksel, Erol Fenercioğlu Özge, Şahin Rahime, Çermik Tevfik Fikret
University of Health Sciences Turkey, İstanbul Bağcılar Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey.
University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Nuclear Medicine, İstanbul, Turkey.
Mol Imaging Radionucl Ther. 2023 Feb 23;32(1):57-61. doi: 10.4274/mirt.galenos.2022.02438.
A 50-year-old man undergone total thyroidectomy and histopathology revealed papillary thyroid carcinoma with a tumor size of 4.5 cm. The patient was referred to a nuclear medicine clinic for radioiodine therapy. Since the thyroglobulin level before the treatment was 495 ug/L, low-dose (185 MBq) I-131 scan was performed. In addition to multiple liver metastases, bone metastases were detected in the sacrum and right 7 rib in I-131 whole body scanning and single photon emission computed tomography/computed tomography (CT) imaging at the time of initial staging. We present a case of multiple metastatic papillary thyroid carcinoma whose radioiodine treatment response and clinical outcome were evaluated with F-fluorodeoxyglucose and Gallium-68 FAPI-04 positron emission tomography/CT.
一名50岁男性接受了全甲状腺切除术，组织病理学显示为甲状腺乳头状癌，肿瘤大小为4.5厘米。该患者被转诊至核医学诊所接受放射性碘治疗。由于治疗前甲状腺球蛋白水平为495μg/L，因此进行了低剂量（185MBq）的I-131扫描。在初始分期时，I-131全身扫描及单光子发射计算机断层扫描/计算机断层扫描（CT）成像显示，除了多发肝转移外，还在骶骨和右侧第7肋骨发现了骨转移。我们报告一例多发转移性甲状腺乳头状癌病例，其放射性碘治疗反应及临床结局通过F-氟脱氧葡萄糖和镓-68 FAPI-04正电子发射断层扫描/CT进行评估。
