Sá Lopes Ramiro, Monteiro Ana Sara, Saez Rosário, Candeias Carlos, Mendonça Catarina
Centro Hospitalar Universitário do Algarve, Faro, Portugal.
Eur J Case Rep Intern Med. 2023 Jan 11;10(1):003721. doi: 10.12890/2023_003712. eCollection 2023.
Early malignant syphilis is an uncommon form of secondary syphilis and characterized by pleomorphic multiple round-to-oval papules, some with necrosis, and associated with systemic signs and symptoms. Usually seen in immunosuppressed patients, mainly those infected with HIV, it can also be observed in immunocompetent patients. We report a case in a young healthy woman with the characteristic features of the disease and with favourable skin lesion evolution after appropriate treatment with penicillin.
Skin lesions can be caused by numerous systemic diseases.Syphilis is the 'great mimicker' and should always be considered as a diagnosis in those with skin lesions.
早期恶性梅毒是二期梅毒的一种罕见形式,其特征为多形性的多个圆形至椭圆形丘疹,部分伴有坏死,并伴有全身症状和体征。通常见于免疫抑制患者,主要是感染HIV的患者,也可见于免疫功能正常的患者。我们报告一例年轻健康女性病例,该病例具有该病的特征性表现,经青霉素适当治疗后皮肤损害演变良好。
皮肤损害可由多种全身性疾病引起。梅毒是“伟大的模仿者”,对于有皮肤损害的患者,应始终将其视为一种诊断考虑。