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恶性梅毒:一例免疫功能正常患者早期二期梅毒的罕见病例。

Malignant Syphilis: A Rare Case of Early Secondary Syphilis in an Immunocompetent Patient.

作者信息

Sá Lopes Ramiro, Monteiro Ana Sara, Saez Rosário, Candeias Carlos, Mendonça Catarina

机构信息

Centro Hospitalar Universitário do Algarve, Faro, Portugal.

出版信息

Eur J Case Rep Intern Med. 2023 Jan 11;10(1):003721. doi: 10.12890/2023_003712. eCollection 2023.

Abstract

UNLABELLED

Early malignant syphilis is an uncommon form of secondary syphilis and characterized by pleomorphic multiple round-to-oval papules, some with necrosis, and associated with systemic signs and symptoms. Usually seen in immunosuppressed patients, mainly those infected with HIV, it can also be observed in immunocompetent patients. We report a case in a young healthy woman with the characteristic features of the disease and with favourable skin lesion evolution after appropriate treatment with penicillin.

LEARNING POINTS

Skin lesions can be caused by numerous systemic diseases.Syphilis is the 'great mimicker' and should always be considered as a diagnosis in those with skin lesions.

摘要

未标注

早期恶性梅毒是二期梅毒的一种罕见形式,其特征为多形性的多个圆形至椭圆形丘疹,部分伴有坏死,并伴有全身症状和体征。通常见于免疫抑制患者,主要是感染HIV的患者,也可见于免疫功能正常的患者。我们报告一例年轻健康女性病例,该病例具有该病的特征性表现,经青霉素适当治疗后皮肤损害演变良好。

学习要点

皮肤损害可由多种全身性疾病引起。梅毒是“伟大的模仿者”,对于有皮肤损害的患者,应始终将其视为一种诊断考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bbf/9930879/19687e3b70cc/3712_Fig1.jpg

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本文引用的文献

1
2020 European guideline on the management of syphilis.2020年欧洲梅毒管理指南。
J Eur Acad Dermatol Venereol. 2021 Mar;35(3):574-588. doi: 10.1111/jdv.16946. Epub 2020 Oct 22.
2
Syphilis Maligna: A Presentation to Bear in Mind.恶性梅毒:需牢记的一种表现。
Actas Dermosifiliogr (Engl Ed). 2019 Apr;110(3):232-237. doi: 10.1016/j.ad.2018.02.024. Epub 2018 Aug 8.
3
Malignant Syphilis in an Immunocompetent Adult Male.免疫功能正常成年男性的恶性梅毒
Indian J Dermatol. 2017 Sep-Oct;62(5):524-527. doi: 10.4103/ijd.IJD_733_16.
4
Early malignant syphilis.早期恶性梅毒
An Bras Dermatol. 2016 Sep-Oct;91(5 suppl 1):148-150. doi: 10.1590/abd1806-4841.20164491.
5
Malignant syphilis in an immunocompetent female patient.一名免疫功能正常女性患者的恶性梅毒。
An Bras Dermatol. 2014 Nov-Dec;89(6):970-2. doi: 10.1590/abd1806-4841.20143155.

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