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臀区原发性默克尔细胞癌小肠转移导致的肠梗阻

Intestinal obstruction due to small intestinal metastasis from primary Merkel cell carcinoma of the gluteal region.

作者信息

Olivos-Gonzales Juan Francisco, Apumayta-Requena Elily, Guevara-Jabiles Andrés, Bravo-Taxa Mercedes

机构信息

Fellow in Abdominal Surgical Oncology, Instituto Nacional de Enfermedades Neoplásicas, Lima 15038, Peru.

https://orcid.org/0000-0002-0559-0295.

出版信息

Ecancermedicalscience. 2022 Dec 19;16:1493. doi: 10.3332/ecancer.2022.1493. eCollection 2022.

Abstract

Merkel cell carcinoma (MCC) is a rare neoplasm of unknown multifactorial origin first described in 1972. It occurs most often in older Caucasian males and is typically associated with sun-exposed areas of skin. However, cases have also been reported in other areas, such as the trunk and the gluteal region. Metastatic disease will occur in up to one-third of cases at onset or during the course of the disease, including metastases to the abdominal organs. We present the case of a 53-year-old male with a history of primary MCC of the right buttock and local resection surgery. Eighteen months later, he presented with a small bowel obstruction and had an emergency segmental bowel resection. Pathology examination with immunohistochemistry concluded that findings were consistent with metastatic MCC.

摘要

默克尔细胞癌(MCC)是一种起源不明的罕见肿瘤,于1972年首次被描述。它最常发生于老年白人男性,通常与皮肤暴露于阳光下的部位有关。然而,其他部位如躯干和臀部区域也有病例报道。高达三分之一的病例在发病时或疾病过程中会发生转移性疾病,包括转移至腹部器官。我们报告一例53岁男性,有右臀部原发性MCC病史并接受了局部切除手术。18个月后,他出现小肠梗阻并接受了急诊节段性肠切除术。免疫组织化学病理检查结果显示与转移性MCC相符。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b351/9935056/e250ca20d6ee/can-16-1493fig1.jpg

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