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¹¹C-蛋氨酸PET/CT与¹⁸F-FDG PET/CT在成人肺泡横纹肌肉瘤评估中的应用

C-Methionine PET/CT and F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma.

作者信息

Hiroshima Yuka, Otomi Yoichi, Shinya Takayoshi, Otsuka Hideki, Harada Masafumi

机构信息

Tokushima University, Department of Radiology, Tokushima, Japan.

出版信息

Mol Imaging Radionucl Ther. 2023 Feb 23;32(1):62-64. doi: 10.4274/mirt.galenos.2022.96977.

DOI:10.4274/mirt.galenos.2022.96977
PMID:36819829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9950675/
Abstract

A 70-year-old man with a tumor in the nasal and paranasal space, was pathologically diagnosed with an alveolar rhabdomyosarcoma, with right cervical lymph node metastasis. Magnetic resonance imaging revealed a primary tumor in the nasal and paranasal sinuses, with associated intracranial infiltration. C-methionine positron emission tomography/computed tomography (PET/CT) revealed increased uptake in the primary tumor and right cervical lymph node metastasis. F-fluorodeoxyglucose PET/CT also revealed increased uptake in the primary tumor and right cervical lymph node. However, the physiological brain uptake overlapped with the primary tumor uptake. Our case suggests the usefulness of C-methionine PET/CT for accurately assessing the extent of alveolar rhabdomyosarcoma, especially in cases with intracranial infiltration or those approximating the brain.

摘要

一名70岁男性,鼻腔和鼻窦区有肿瘤,经病理诊断为腺泡状横纹肌肉瘤,伴有右侧颈部淋巴结转移。磁共振成像显示鼻腔和鼻窦有原发性肿瘤,并伴有颅内浸润。碳-蛋氨酸正电子发射断层扫描/计算机断层扫描(PET/CT)显示原发性肿瘤和右侧颈部淋巴结转移灶摄取增加。氟-氟脱氧葡萄糖PET/CT也显示原发性肿瘤和右侧颈部淋巴结摄取增加。然而,生理性脑摄取与原发性肿瘤摄取重叠。我们的病例表明,碳-蛋氨酸PET/CT对于准确评估腺泡状横纹肌肉瘤的范围很有用,特别是在有颅内浸润或接近脑部的病例中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/a3e4523838ed/MIRT-32-62-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/2a9951d37802/MIRT-32-62-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/dd98d5f7374c/MIRT-32-62-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/a3e4523838ed/MIRT-32-62-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/2a9951d37802/MIRT-32-62-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/dd98d5f7374c/MIRT-32-62-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/891d/9950675/a3e4523838ed/MIRT-32-62-g3.jpg

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Diagnostic accuracy of N-ammonia PET, C-methionine PET and F-fluorodeoxyglucose PET: a comparative study in patients with suspected cerebral glioma.
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