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一系列颅内病变患者中（11）C-蛋氨酸正电子发射断层扫描的影像谱及陷阱

Imaging Spectrum and Pitfalls of (11)C-Methionine Positron Emission Tomography in a Series of Patients with Intracranial Lesions.

作者信息

Ito Kimiteru, Matsuda Hiroshi, Kubota Kazoo

机构信息

Department of Radiology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo 173-0015, Japan.

Integrative Brain Imaging Center, National Center of Neurology and Psychiatry, Tokyo 187-8551, Japan.

出版信息

Korean J Radiol. 2016 May-Jun;17(3):424-34. doi: 10.3348/kjr.2016.17.3.424. Epub 2016 Apr 14.

DOI:10.3348/kjr.2016.17.3.424
PMID:27134530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4842861/
Abstract

(11)C-methionine (Met) positron emission tomography (PET) is one of the most commonly used PET tracers for evaluating brain tumors. However, few reports have described tips and pitfalls of (11)C-Met PET for general practitioners. Physiological (11)C-Met uptake, anatomical variations, vascular disorders, non-tumorous lesions such as inflammation or dysplasia, benign brain tumors and patient condition during (11)C-Met PET examination can potentially affect the image interpretation and cause false positives and negatives. These pitfalls in the interpretation of (11)C-Met PET images are important for not only nuclear medicine physicians but also general radiologists. Familiarity with the spectrum and pitfalls of (11)C-Met images could help prevent unfavorable clinical results caused by misdiagnoses.

摘要

碳-11蛋氨酸（Met）正电子发射断层扫描（PET）是评估脑肿瘤最常用的PET示踪剂之一。然而，针对全科医生的碳-11蛋氨酸PET的技巧和陷阱的报道很少。生理性碳-11蛋氨酸摄取、解剖变异、血管疾病、非肿瘤性病变（如炎症或发育异常）、良性脑肿瘤以及碳-11蛋氨酸PET检查期间的患者状况都可能影响图像解读，并导致假阳性和假阴性。碳-11蛋氨酸PET图像解读中的这些陷阱不仅对核医学医生很重要，对普通放射科医生也很重要。熟悉碳-11蛋氨酸图像的范围和陷阱有助于预防因误诊导致的不良临床结果。

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