巴西东南部 COVID-19 大流行期间的毛霉菌病住院人数增加：2010-2021 年时间序列。
Increase in mucormycosis hospitalizations in southeastern Brazil during the COVID-19 pandemic: a 2010-2021 time series.
机构信息
Pontifícia Universidade Católica de Campinas, Faculdade de Medicina, Campinas, SP, Brasil.
Pontifícia Universidade Católica de Campinas, Hospital da PUC-Campinas, Departamento de Infectologia, Campinas, SP, Brasil.
出版信息
Rev Soc Bras Med Trop. 2023 Feb 20;56:e0333. doi: 10.1590/0037-8682-0333-2022. eCollection 2023.
BACKGROUND
Mucormycosis is a severe invasive fungal disease. During the coronavirus disease 2019 (COVID-19) pandemic, outbreaks have been reported worldwide, but epidemiological studies are still scarce in Brazil.
METHODS
We conducted a time-series cohort hospitalization study (2010-2021) in southeastern Brazil.
RESULTS
There were 311 cases (85 during the pandemic), with significant (P < 0.05) involvement of patients older than 40 years (84%), white patients (78%), rhinocerebral site (63%), and São Paulo State residents (84%).
CONCLUSIONS
Mucormycosis hospitalizations were highly prevalent. Further studies are needed to assess the burden of COVID-19 on mucormycosis in Brazil.
背景
毛霉菌病是一种严重的侵袭性真菌感染。在 2019 年冠状病毒病（COVID-19）大流行期间，世界各地都有暴发的报告，但在巴西，流行病学研究仍然很少。
方法
我们在巴西东南部进行了一项时间序列队列住院研究（2010-2021 年）。
结果
共有 311 例病例（大流行期间 85 例），40 岁以上患者（84%）、白人患者（78%）、鼻颅部位（63%）和圣保罗州居民（84%）的参与率显著（P<0.05）。
结论
毛霉菌病的住院率很高。需要进一步研究来评估 COVID-19 对巴西毛霉菌病的负担。
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