Rolbin S H, Levinson G, Shnider S M, Biehl D R, Wright R G
Anesthesiology. 1979 Jul;51(1):37-40.
In seven pregnant ewes, 3--5 min of hypotension resulting from spinal anesthesia decreased uterine blood flow 17 per cent. Dopamine, in doses sufficient to maintain blood pressure at control values (20--40 micrgram/kg/min) for 3--5 min, further decreased uterine blood flow to 56 per cent less than control and increased uterine vascular resistance to 50 per cent more than control. Following 30 min of hypotension, 30 min of dopamine administration in doses sufficient to restore blood pressure to control values (5--20 microgram/kg/min) similarly decreased uterine blood flow to 29 per cent less than control and increased uterine vascular resistance to 35 per cent more than control.
在7只怀孕母羊中，脊髓麻醉导致的3 - 5分钟低血压使子宫血流量减少了17%。多巴胺剂量足以在3 - 5分钟内将血压维持在对照值（20 - 40微克/千克/分钟），进一步使子宫血流量降至比对照低56%，并使子宫血管阻力比对照增加50%。在30分钟低血压后，以足以将血压恢复到对照值（5 - 20微克/千克/分钟）的剂量给予30分钟多巴胺，同样使子宫血流量降至比对照低29%，并使子宫血管阻力比对照增加35%。
