Gen Dent. 2023 Mar-Apr;71(2):70-74.
Erythema multiforme (EM) is a rare immune-mediated reaction with mucocutaneous involvement. This case report describes the development of EM in a 9-year-old girl after treatment with imiquimod, a topical immunomodulator used in the management of some dermatologic conditions. Because imiquimod-related EM is rare, particularly in children, this article also reviews the potential adverse effects of this drug and the main characteristics of imiquimod-induced EM, especially in similar cases reported in the literature. Clinicians should be aware that topical imiquimod can induce EM, and this medication should be added to the extensive list of drugs that can trigger the condition.
多形红斑（EM）是一种罕见的免疫介导的黏膜皮肤受累反应。本病例报告描述了一例 9 岁女孩在使用咪喹莫特（一种用于治疗某些皮肤病的局部免疫调节剂）治疗后发生 EM 的情况。由于咪喹莫特相关 EM 较为罕见，特别是在儿童中，本文还回顾了该药物的潜在不良反应以及咪喹莫特诱导的 EM 的主要特征，尤其是在文献中报道的类似病例。临床医生应意识到，局部咪喹莫特可诱导 EM，应将该药物添加到可引发该疾病的广泛药物清单中。
