Department of Oncological and Interventional Radiology, Businco Hospital, Via Edward Jenner 1, 09121 Cagliari, Italy.
Department of Radiology, Hospital del Mar, Pg. Marítim de la Barceloneta, 25, 29, 08003 Barcelona, Spain.
Curr Oncol. 2023 Jan 30;30(2):1663-1672. doi: 10.3390/curroncol30020127.
(1) Background: The aim of this study was to retrospectively evaluate the safety and efficacy of a combined CT-guided percutaneous microwave ablation (MWA) and pedicle screw fixation followed by vertebroplasty (MASFVA) for the treatment and stabilization of painful vertebral metastases with vertebral pedicle involvement. (2) Methods: from January 2013 to January 2017 11 patients with 16 vertebral metastatic lesions (7 men and 5 women; mean age, 65 ± 11 years) with vertebral metastases underwent CT-guided microwave ablation and screw fixation followed by vertebroplasty (MASFVA). Technical success, complication rate, pain evaluation using a visual analogue scale (VAS), Oswestry Disability Index (ODI) and local tumor control were examined. (3) Results: Technical success rate was 100%. No procedure-related major complications occurred. VAS score decreased from 6.8 ± 0.7 to 0.6 ± 0.6. ODI score decreased from 3.1 ± 0.7 to 1.2 ± 0.4. All patients could walk independently without neurological complication after one week from the procedure. No new bone fractures or local disease recurrence occurred during a median follow-up of 12 months. (4) Conclusions: Our results suggest that MWA and percutaneous pedicle screw fixation followed by vertebroplasty for the treatment of painful vertebral metastases is a safe and effective procedure for painful vertebral metastases with vertebral pedicle involvement, allowing pain relief and local tumor control.
(1)背景:本研究旨在回顾性评估 CT 引导下经皮微波消融(MWA)联合椎弓根螺钉固定后骨水泥强化(MASFVA)治疗和稳定伴有椎弓根受累的疼痛性椎体转移瘤的安全性和有效性。(2)方法:自 2013 年 1 月至 2017 年 1 月,11 例 16 个椎体转移病灶(7 例男性,5 例女性;平均年龄 65±11 岁)的患者接受了 CT 引导下微波消融和螺钉固定后骨水泥强化(MASFVA)治疗。检查技术成功率、并发症发生率、采用视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)评估疼痛、局部肿瘤控制情况。(3)结果:技术成功率为 100%。无与手术相关的严重并发症。VAS 评分从 6.8±0.7 降至 0.6±0.6。ODI 评分从 3.1±0.7 降至 1.2±0.4。所有患者在术后一周内均可独立行走,无神经并发症。在中位随访 12 个月期间,无新发骨折或局部疾病复发。(4)结论:我们的结果表明,对于伴有椎弓根受累的疼痛性椎体转移瘤,MWA 和经皮椎弓根螺钉固定后骨水泥强化治疗是一种安全有效的方法,可缓解疼痛,控制局部肿瘤。