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立体定向体部放疗治疗肝细胞癌:简要概述。

Stereotactic Body Radiotherapy for Hepatocellular Carcinoma: A Brief Overview.

机构信息

Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.

出版信息

Curr Oncol. 2023 Feb 18;30(2):2493-2500. doi: 10.3390/curroncol30020190.

DOI:10.3390/curroncol30020190
PMID:36826151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9956001/
Abstract

Stereotactic body radiotherapy (SBRT), a type of external beam radiotherapy, yields local control of hepatocellular carcinoma (HCC) at rates as high as 90%. SBRT has been recognized as an alternative therapy for patients for whom standard modalities such as surgery (resection or transplantation) or ablation are deemed unsuitable. SBRT has the potential to improve the prognosis of HCC, as it can be used as an adjunct to other treatment modalities. The assessment of post-SBRT images of the treated tumor and surrounding normal liver tissue requires special attention. Future research is warranted to determine how best to use SBRT versus other therapies and how to combine them.

摘要

立体定向体部放射治疗(SBRT)是一种外照射放疗,其治疗肝细胞癌(HCC)的局部控制率高达 90%。SBRT 已被认为是一种替代疗法,适用于那些不适合采用标准方法(如手术切除或移植)或消融治疗的患者。SBRT 有可能改善 HCC 的预后,因为它可以作为其他治疗方式的辅助手段。对接受 SBRT 治疗后的肿瘤和周围正常肝组织的图像进行评估需要特别注意。未来需要开展研究,以确定如何最好地使用 SBRT 与其他疗法以及如何将它们结合使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6702/9956001/19918fcf3474/curroncol-30-00190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6702/9956001/19918fcf3474/curroncol-30-00190-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6702/9956001/19918fcf3474/curroncol-30-00190-g001.jpg

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2
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Hepatol Res. 2022 Apr;52(4):329-336. doi: 10.1111/hepr.13746. Epub 2022 Feb 22.
3
BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update.
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4
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6
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