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1935年至1972年期间选定的12年里,波士顿市医院因菌血症感染的住院时长。

Duration of hospitalization for bacteremic infections at Boston City Hospital during 12 selected years between 1935 and 1972.

作者信息

Finland M, Barnes M W

出版信息

J Infect Dis. 1978 Dec;138(6):837-48. doi: 10.1093/infdis/138.6.837.

Abstract

In survivors of both community-acquired (CA) and hospital-acquired (HA) bacteremic infections at Boston City Hospital during 12 selected years between 1935 and 1972, the mean hospital stay fluctuated widely from one selected year to the next, but it was generally shorter and early discharges were more frequent in the years when effective antibacterial agents were used. The greatest reduction in hospital stay occurred by 1941. The size of the fluctuations and reductions also varied with the causative organism. The average duration of hospitalization of all survivors of HA bacteremic infections after the first positive blood culture was 10.5 days longer than the total hospitalization of survivors of CA infections. The reduced length of hospital stay after 1935 is attributed to the successful use of effective antibacterial drugs, and the greater effect in CA than in HA cases is attributed to more frequent infections in the latter with organisms resistant to those drugs.

摘要

在1935年至1972年间选定的12年里,波士顿市医院社区获得性(CA)和医院获得性(HA)菌血症感染的幸存者中,平均住院时间在不同选定年份波动很大,但在使用有效抗菌药物的年份,住院时间通常较短,提前出院更为频繁。到1941年,住院时间缩短幅度最大。波动和缩短的幅度也因致病微生物而异。首次血培养呈阳性后,HA菌血症感染所有幸存者的平均住院时间比CA感染幸存者的总住院时间长10.5天。1935年后住院时间的缩短归因于有效抗菌药物的成功使用,而CA病例比HA病例效果更显著归因于后者感染对这些药物耐药的微生物更为频繁。

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