Ding Xiangchao, Sun Bing, Liu Liang, Lei Yuan, Su Yunshu
Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430064, China.
Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, China.
J Cardiovasc Dev Dis. 2023 Feb 8;10(2):73. doi: 10.3390/jcdd10020073.
Postoperative tracheostomy (POT) is an important indicator of critical illness, associated with poorer prognoses and increased medical burdens. However, studies on POTs after heart valve surgery (HVS) have not been reported. The objectives of this study were first to identify the risk factors and develop a risk prediction model for POTs after HVS, and second to clarify the relationship between POTs and clinical outcomes. Consecutive adults undergoing HVS from January 2016 to December 2019 in a single cardiovascular center were enrolled, and a POT was performed in 1.8% of the included patients (68/3853). Compared to patients without POTs, the patients with POTs had higher rates of readmission to the ICU and in-hospital mortality, as well as longer ICU and hospital stays. Five factors were identified to be significantly associated with POTs after HVS by our multivariate analysis, including age, diabetes mellitus, pulmonary edema, intraoperative transfusion of red blood cells, and surgical types. A nomogram and a risk calculator were constructed based on the five factors, showing excellent discrimination, calibration, and clinical utility. Three risk intervals were defined as low-, medium-, and high-risk groups according to the nomogram and clinical practice. The findings of this study may be helpful for early risk assessment and perioperative management.
术后气管切开术(POT)是危重病的一项重要指标,与较差的预后和增加的医疗负担相关。然而,关于心脏瓣膜手术(HVS)后POT的研究尚未见报道。本研究的目的,一是确定HVS后POT的危险因素并建立风险预测模型,二是阐明POT与临床结局之间的关系。纳入了2016年1月至2019年12月在单一心血管中心接受HVS的连续成年患者,纳入患者中有1.8%(68/3853)进行了POT。与未行POT的患者相比,行POT的患者入住重症监护病房(ICU)和院内死亡的发生率更高,ICU和住院时间也更长。通过多因素分析确定了五个与HVS后POT显著相关的因素,包括年龄、糖尿病、肺水肿、术中输注红细胞和手术类型。基于这五个因素构建了列线图和风险计算器,显示出良好的区分度、校准度和临床实用性。根据列线图和临床实践将三个风险区间定义为低、中、高风险组。本研究结果可能有助于早期风险评估和围手术期管理。