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肉毒毒素 B 在局限性多汗症中的疗效和安全性:叙事性综述。

Efficacy and Safety of Botulinum Toxin B in Focal Hyperhidrosis: A Narrative Review.

机构信息

Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60121 Ancona, Italy.

出版信息

Toxins (Basel). 2023 Feb 11;15(2):147. doi: 10.3390/toxins15020147.

DOI:10.3390/toxins15020147
PMID:36828461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9966525/
Abstract

Botulinum toxin type B (BoNT-B), known as Myobloc in the United States and as Neurobloc in Europe, is a new therapeutically available serotype among the botulinum toxin family. During the last years several data have been reported in literature investigating its efficacy and safety, as well as defining the dosing and application regiments of BoNT-B in the treatment of hyperhidrosis. Moreover, recent studies have been examining its safety profile, which may be different from those known about BoNT-A. The aim of this review is to provide information about what is currently known about BoNT-B in regards to the treatment of focal hyperhidrosis.

摘要

肉毒杆菌毒素 B 型(BoNT-B),在美国被称为 Myobloc,在欧洲被称为 Neurobloc,是肉毒毒素家族中一种新的可治疗的血清型。在过去的几年中,文献中报道了多项关于其疗效和安全性的研究,以及确定 BoNT-B 治疗多汗症的剂量和应用方案。此外,最近的研究还在检查其安全性概况,这可能与已知的 BoNT-A 不同。本综述的目的是提供关于 BoNT-B 在治疗局限性多汗症方面的最新信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2655/9966525/878e571c1aea/toxins-15-00147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2655/9966525/878e571c1aea/toxins-15-00147-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2655/9966525/878e571c1aea/toxins-15-00147-g001.jpg

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本文引用的文献

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Hyperhidrosis of the residual limb: a narrative review of the measurement and treatment of excess perspiration affecting individuals with amputation.残肢多汗症:对影响截肢者的过量出汗的测量和治疗的叙述性综述。
Prosthet Orthot Int. 2021 Dec 1;45(6):477-486. doi: 10.1097/PXR.0000000000000040.
2
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.PRISMA 2020 声明:系统评价报告的更新指南。
BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71.
3
Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review.
肉毒毒素在皮肤科的治疗用途:系统评价。
Toxins (Basel). 2021 Feb 5;13(2):120. doi: 10.3390/toxins13020120.
4
Postmenopausal craniofacial hyperhidrosis treated with botulinum toxin type B.绝经后颅面多汗症采用肉毒毒素 B 治疗。
J Dermatol. 2019 Oct;46(10):874-878. doi: 10.1111/1346-8138.15029. Epub 2019 Aug 2.
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Botulinum Toxin Off-Label Use in Dermatology: A Review.肉毒杆菌毒素在皮肤科的非标签使用:综述
Skin Appendage Disord. 2017 Mar;3(1):39-56. doi: 10.1159/000452341. Epub 2017 Feb 1.
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Residual Limb Hyperhidrosis and RimabotulinumtoxinB: A Randomized Placebo-Controlled Study.残肢多汗症与利美布汀毒素B:一项随机安慰剂对照研究
Arch Phys Med Rehabil. 2016 May;97(5):659-664.e2. doi: 10.1016/j.apmr.2015.12.027. Epub 2016 Jan 23.
7
Clinical differences between botulinum neurotoxin type A and B.A型与B型肉毒杆菌神经毒素的临床差异。
Toxicon. 2015 Dec 1;107(Pt A):77-84. doi: 10.1016/j.toxicon.2015.08.001. Epub 2015 Aug 7.
8
Treatment of compensatory hyperhidrosis after sympathectomy with botulinum toxin and anticholinergics.交感神经切断术后肉毒毒素和抗胆碱能药物治疗代偿性多汗症。
Clin Auton Res. 2015 Jun;25(3):161-7. doi: 10.1007/s10286-015-0278-x. Epub 2015 Mar 14.
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