Surgical options for treating ventricular tachyarrhythmia and sudden death.

From 1981 to 1987, 62 patients with ventricular tachyarrhythmias and associated sudden death required treatment after unsuccessful initial medical therapy (51 patients) and previous surgical therapy (11 patients). Surgical options included direct revascularization (group I, 11 patients), endocardial resection (group II, 7 patients), automatic internal cardiac defibrillators (group III, 18 patients), and these combinations of operations: revascularization and endocardial resection (group IV, 18 patients), revascularization and insertion of automatic internal cardiac defibrillators (group V, 5 patients), and endocardial resection and insertion of cardiac defibrillator (group VI, 3 patients). Five underwent repeat revascularization (4) or endocardial resection (4) with mitral valve replacement (1) or papillary muscle reconstruction (2). The overall operative mortality of 8.1% (5/62) has been acceptable (2.8% or 1/36 for the simple procedures [groups I, II, and III] and 15.4% or 4/26 for the combined procedures [IV, V, and VI]; p less than 0.074). Operative risk factors included recent myocardial infarction (4/5 deaths) and depressed ejection fraction of 23% or less (5/5 deaths). These operative risks were highest in group IV and, thus, the highest mortality was in group IV (4/18 patients or 22%, p less than 0.022). Six late deaths (4 patients in group III) brought the overall survival rate to 82% or 51/62 patients at a mean follow-up of 30 months. Surgical treatment of sudden death ventricular tachyarrhythmias requires a planned, combined operative approach, since initial medical or surgical failures can occur. The optimal surgical approach requires complete revascularization, resection of the localized subendocardial arrhythmogenic focus, and ventricular reconstruction. An automatic defibrillator is a palliative alternative for less favorable surgical anatomy and for patients who are poor operative candidates for these combined or reoperative procedures.