Sanches Matheus Silva, Silva Luana Carvalho, Silva Caroline Rodrigues da, Montini Victor Hugo, Oliva Bruno Henrique Dias de, Guidone Gustavo Henrique Migliorini, Nogueira Mara Corrêa Lelles, Menck-Costa Maísa Fabiana, Kobayashi Renata Katsuko Takayama, Vespero Eliana Carolina, Rocha Sergio Paulo Dejato
Laboratory of Bacteriology, Center of Biological Sciences, Department of Microbiology, State University of Londrina, Londrina P.O. Box 10.011, Brazil.
Microorganism Research Center, Health Sciences Center, Department of Dermatological, Infectious and Parasitic Diseases, Medical School of São José do Rio Preto, São José do Rio Preto P.O. Box 15.090, Brazil.
Antibiotics (Basel). 2023 Feb 10;12(2):370. doi: 10.3390/antibiotics12020370.
The present study aimed to evaluate the prevalence of antimicrobial resistance and clonal relationships in isolated from chicken meat, beef, pork, and community-acquired urinary tract infections (UTI-CA). Chicken meat isolates showed the highest multidrug resistance (MDR), followed by those from pork and UTI-CA, whereas beef had relatively few MDR strains. All sources had strains that carried , whereas and were only detected in chicken meat and UTI-CA isolates. This indicates that chicken meat should be considered an important risk factor for the spread of carrying and . Furthermore, ESBL/AmpC producing strains were resistant to a greater number of antimicrobials and possessed more resistance genes than non-producing strains. In addition, the antimicrobial resistance genes , , , , , and were also found. Molecular typing showed a genetic similarity between chicken meat and UTI-CA isolates, including some strains with 100% similarity, indicating that chicken can be a source of causing UTI-CA. It was concluded that meat, especially chicken meat, can be an important source of dissemination of multidrug-resistant in the community.
本研究旨在评估从鸡肉、牛肉、猪肉以及社区获得性尿路感染（UTI-CA）中分离出的[具体内容缺失]的耐药性流行情况和克隆关系。鸡肉分离株显示出最高的多重耐药性（MDR），其次是猪肉和UTI-CA分离株，而牛肉的多重耐药菌株相对较少。所有来源都有携带[具体内容缺失]的菌株，而[具体内容缺失]仅在鸡肉和UTI-CA分离株中检测到。这表明鸡肉应被视为携带[具体内容缺失]的[具体内容缺失]传播的重要危险因素。此外，产ESBL/AmpC的菌株比不产ESBL/AmpC的菌株对更多种类的抗菌药物耐药，且拥有更多耐药基因。另外，还发现了抗菌耐药基因[具体基因名称缺失]。分子分型显示鸡肉和UTI-CA分离株之间存在遗传相似性，包括一些相似度达100%的菌株，这表明鸡肉可能是导致UTI-CA的[具体内容缺失]的来源。研究得出结论，肉类，尤其是鸡肉，可能是社区中多重耐药[具体内容缺失]传播的重要来源。
