Xie Yunfei, Dong Xianghui, Cai Nifei, Yang Fangwei, Yao Weirong, Huang Lijun
State Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, China.
School of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, China.
Foods. 2023 Feb 14;12(4):813. doi: 10.3390/foods12040813.
Bisphenol A (BPA) is an endocrine disruptor which is widely present in fish under the influence of environmental pollution. It is essential to establish a rapid detection method for BPA. Zeolitic imidazolate framework (ZIF-8) is a typical metal-organic framework material (MOFs) with a strong adsorption capacity, which can effectively adsorb harmful substances in food. Combining MOFs and surface-enhanced Raman spectroscopy (SERS) can achieve rapid and accurate screening of toxic substances. In this study, a rapid detection method for BPA was established by preparing a new reinforced substrate Au@ZIF-8. The SERS detection method was optimized by combining SERS technology with ZIF-8. The Raman peak at 1172 cm was used as the characteristic quantitative peak, and the lowest detection concentration of BPA was as low as 0.1 mg/L. In the concentration range of 0.1~10 mg/L, the linear relationship between SERS peak intensity and the concentration of BPA was good, and R was 0.9954. This novel SERS substrate was proven to have great potential in rapidly detecting BPA in food.
双酚A（BPA）是一种内分泌干扰物，在环境污染的影响下广泛存在于鱼类中。建立一种快速检测双酚A的方法至关重要。沸石咪唑酯骨架材料（ZIF-8）是一种典型的具有强大吸附能力的金属有机骨架材料（MOFs），它能够有效吸附食品中的有害物质。将金属有机骨架材料与表面增强拉曼光谱（SERS）相结合，可以实现对有毒物质的快速、准确筛选。在本研究中，通过制备新型增强基底Au@ZIF-8建立了一种双酚A的快速检测方法。通过将表面增强拉曼光谱技术与ZIF-8相结合优化了表面增强拉曼光谱检测方法。将1172 cm处的拉曼峰用作特征定量峰，双酚A的最低检测浓度低至0.1 mg/L。在0.1~10 mg/L的浓度范围内，表面增强拉曼光谱峰强度与双酚A浓度之间的线性关系良好，相关系数R为0.9954。这种新型表面增强拉曼光谱基底被证明在快速检测食品中的双酚A方面具有巨大潜力。
