Whelton P K, Russell R P, Harrington D P, Williams G M, Walker W G
JAMA. 1979 Mar 16;241(11):1128-31.
During a five-year period, we studied 21 of 319 renal transplant recipients who were admitted for evaluation of refractory hypertension. For comparison we examined 93 consecutive patients in the renal transplant clinic. Hypertension, which was noted in 47% of the outpatients, occurred with greater frequency following renal transplantation from cadaveric donors and was associated with a decline in renal function. The 21 inpatients had higher blood pressures and were studied at an earlier stage than their outpatient counterparts. Fourteen of the inpatients had underlying stenosis of their transplant artery nd revascularization of the transplanted kidney was possible in the majority of these patients. Stenosis of the transplant artery was suggested by the occurrence of severe hypertension during the first year following transplantation, a bruit in the transplant region, and increased levels of peripheral plasma renin activity.
在五年期间，我们研究了319名因难治性高血压入院评估的肾移植受者中的21名。作为对照，我们检查了肾移植门诊的93例连续患者。门诊患者中47% 存在高血压，尸体供肾肾移植后高血压发生率更高，且与肾功能下降有关。21名住院患者血压更高，且比门诊患者在更早阶段接受研究。14名住院患者存在移植肾动脉潜在狭窄，这些患者中的大多数可行移植肾血管重建。移植后第一年出现严重高血压、移植区域有杂音以及外周血浆肾素活性水平升高提示移植肾动脉狭窄。
