Hesp W L, Wobbes T, Postma M H
Department of General Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands.
Neth J Surg. 1987 Aug;39(4):125-8.
From 1956 to 1985, 38 patients with a carcinoid of the intestine were treated. Tumours originating from the duodenum, ileum and colon had the worst prognosis. Fourteen out of 15 patients showed lymph-node metastases, and eight liver secondaries. Metastatic spread was rare (9%) if the primary tumour was small or an incidental finding (appendix). Even with metastatic spread there may be a longer survival due to the slow growth pattern of carcinoid metastases, which often become manifest several years after resection of the primary tumour. Metachronous liver metastases should be considered for surgical resection. Three of the 38 patients suffered from a carcinoid syndrome.
1956年至1985年期间，对38例肠道类癌患者进行了治疗。起源于十二指肠、回肠和结肠的肿瘤预后最差。15例患者中有14例出现淋巴结转移，8例出现肝转移。如果原发性肿瘤较小或为偶然发现（阑尾），转移扩散很少见（9%）。即使发生转移扩散，由于类癌转移的生长模式缓慢，生存期可能更长，类癌转移通常在原发性肿瘤切除数年之后才会显现。异时性肝转移应考虑手术切除。38例患者中有3例患有类癌综合征。
