Chanaud C M, Das G D
Department of Biological Sciences, Lily Hall of Life Sciences, Purdue University, W. Lafayette, IN 47907.
Neurosci Lett. 1987 Sep 23;80(2):127-33. doi: 10.1016/0304-3940(87)90641-0.
Interactions between growth potential (as related to the age of donor embryos and type of tissue), initial volume, and fresh vs frozen conditions of neural transplants were studied in rats. Neural tissues with high growth potential (16-day gestation neocortical tissue) when used fresh yielded the best growth of the transplants, which was positively related to the initial volume of the tissue. At the other extreme, neural tissues with very low growth potential when used following their freezing and thawing yielded the poorest results. Changes in the initial volume of transplants did not seem to improve the final growth. Combination of these variables in between these two extremes yielded transplants of variable sizes.
在大鼠中研究了生长潜力（与供体胚胎年龄和组织类型有关）、初始体积以及神经移植新鲜与冷冻条件之间的相互作用。具有高生长潜力的神经组织（妊娠16天的新皮质组织）新鲜使用时，移植组织生长最佳，且与组织的初始体积呈正相关。另一方面，生长潜力非常低的神经组织在冷冻和解冻后使用时，效果最差。移植组织初始体积的变化似乎并未改善最终的生长情况。在这两个极端情况之间组合这些变量，会产生大小各异的移植组织。
