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中国腹腔镜与传统开放腹膜透析导管置入术的Meta分析

Laparoscopic versus Conventional Open Peritoneal Dialysis Catheter Insertion in China: A Meta-Analysis.

作者信息

Lu Macheng, Cheng Cong, Zhang Ye

机构信息

Department of General Surgery, Nanjing Medical University Affiliated Wuxi people's Hospital, Wuxi, Jiangsu Province, China.

出版信息

Urol J. 2023 Feb 27;20(2):81-89. doi: 10.22037/uj.v20i.7359.

Abstract

PURPOSE

To compare the risk of complications between laparoscopic peritoneal dialysis (PD) catheter placement and open PD catheter placement.

METHODS

We searched numerous databases, including SinoMed, CNKI, cqVIP, WanFang, Pubmed, Web of Science, OVID,  Cochrane and Scopus, for published randomized controlled trials (RCTs) and non-randomized controlled trials (non-RCTs) .

RESULTS

Ten studies were included(n=1341). The overall statistical results showed that patients receiving laparoscopic insertion of the PD catheter had a lower risk of catheter migration, inadequate drainage and blockage. The risk of leakage was higher in the laparoscopic group in studies performed prior to 2015; in studies performed after 2015, the risk of leakage was lower than in the conventional open-placement group. For the risk of developing pain, the risk was lower in the subgroup of laparoscopic patients starting PD within 1 day after catheter insertion; however, there was no significant difference between the subgroups starting PD 1 week or 2 weeks after catheter insertion. The risk outcome for abdominal bleeding was similar to that for pain, with a lower risk in the subgroup of laparoscopic patients starting PD within 1 day. The overall research quality was moderate.

CONCLUSION

Laparoscopic placement of the PD catheter has unique advantages over conventional open surgical placement, especially in special conditions such as emergency initiation. In addition, we found that some factors that were previously considered irrelevant may have an impact on the results for Asians. However, this conclusion still needs to be substantiated by further large samples in multicenter, high quality Randomized Controlled Trials (RCTs).

摘要

目的

比较腹腔镜腹膜透析(PD)导管置入术与开放性PD导管置入术的并发症风险。

方法

我们检索了多个数据库,包括中国生物医学文献数据库、中国知网、维普资讯、万方数据、PubMed、Web of Science、OVID、Cochrane和Scopus,以查找已发表的随机对照试验(RCT)和非随机对照试验(非RCT)。

结果

纳入10项研究(n = 1341)。总体统计结果显示,接受腹腔镜PD导管置入术的患者发生导管移位、引流不畅和堵塞的风险较低。在2015年之前进行的研究中,腹腔镜组的渗漏风险较高;在2015年之后进行的研究中,腹腔镜组的渗漏风险低于传统开放置入组。对于疼痛发生风险,在导管插入后1天内开始进行PD的腹腔镜患者亚组中风险较低;然而,在导管插入后1周或2周开始进行PD的亚组之间没有显著差异。腹部出血的风险结果与疼痛相似,在导管插入后1天内开始进行PD的腹腔镜患者亚组中风险较低。总体研究质量中等。

结论

腹腔镜PD导管置入术相对于传统开放手术置入术具有独特优势,尤其是在紧急启动等特殊情况下。此外,我们发现一些先前认为无关的因素可能会对亚洲人的结果产生影响。然而,这一结论仍需通过进一步的多中心、高质量随机对照试验(RCT)大样本研究来证实。

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