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与外侧半规管骨岛中央透亮区相关的先天性重度至极重度感音神经性听力损失的研究

Research on congenital severe-to-profound sensorineural hearing loss associated with central lucency of the bony island of the lateral semicircular canal.

作者信息

Wang Qin, Bian Panpan, Bai Shengjin, Chen Chi, Wang Yanli, Guo Yufen, Xu Baicheng

机构信息

Department of Otolaryngology-Head & Neck Surgery, Lanzhou University Second Hospital, Lanzhou, China.

出版信息

Acta Otolaryngol. 2023 Feb;143(2):134-140. doi: 10.1080/00016489.2023.2179661. Epub 2023 Feb 25.

DOI:10.1080/00016489.2023.2179661
PMID:36840650
Abstract

BACKGROUND

Central lucency of the bony island of the lateral semicircular canal (LSCC) is commonly found in patients with congenital severe-to-profound sensorineural hearing loss (SNHL).

OBJECTIVE

Exploring the significance of bony island lucency of LSCC in congenital severe-to-profound SNHL patients.

MATERIAL AND METHODS

Retrospective measurements of the inner ear structures were made on axial temporal bone CT scans from 182 (364 ears) congenital severe-to-profound SNHL patients and 50 (100 ears) tympanic membrane perforation (TMP) patients.

RESULTS

The incidence of bony island lucency of LSCC was 46.7% in the congenital severe-to-profound SNHL group and 0% in the TMP group. There was a statistically significant difference in inner ear structures among congenital severe-to-profound SNHL patients with normal inner ear structure and bony island lucency of LSCC, congenital severe-to-profound SNHL patients with normal inner ear structure and no bony island lucency of LSCC, and TMP patients. The importance of the bony island lucency of LSCC was further confirmed through multiple linear regression analysis.

CONCLUSIONS AND SIGNIFICANCE

Bony island lucency may have significance in congenital severe-to-profound SNHL and may be a manifestation of largely overlooked SCC malformation or hypoplasia of the inner ear.

摘要

背景

先天性重度至极重度感音神经性听力损失(SNHL)患者中常见外侧半规管(LSCC)骨岛中心透亮。

目的

探讨LSCC骨岛透亮在先天性重度至极重度SNHL患者中的意义。

材料与方法

对182例(364耳)先天性重度至极重度SNHL患者和50例(100耳)鼓膜穿孔(TMP)患者的颞骨轴向CT扫描进行内耳结构的回顾性测量。

结果

先天性重度至极重度SNHL组中LSCC骨岛透亮的发生率为46.7%,TMP组为0%。内耳结构在具有正常内耳结构且LSCC有骨岛透亮的先天性重度至极重度SNHL患者、具有正常内耳结构且LSCC无骨岛透亮的先天性重度至极重度SNHL患者以及TMP患者之间存在统计学显著差异。通过多元线性回归分析进一步证实了LSCC骨岛透亮的重要性。

结论与意义

骨岛透亮可能在先天性重度至极重度SNHL中具有意义,可能是内耳很大程度上被忽视的半规管畸形或发育不全的一种表现。

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