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足月外倒转术:是否需要使用宫缩抑制剂?

External cephalic version at term: is a tocolytic necessary?

作者信息

Robertson A W, Kopelman J N, Read J A, Duff P, Magelssen D J, Dashow E E

机构信息

Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, Washington.

出版信息

Obstet Gynecol. 1987 Dec;70(6):896-9.

PMID:3684126
Abstract

This prospective investigation evaluates the benefit of a beta-mimetic tocolytic for external cephalic version. From July 1, 1984 to May 15, 1987, 58 patients who had breech presentations between 37-41 weeks' gestation were considered for external cephalic version. The patients were randomly assigned to one of two groups: tocolytic or no tocolytic. An ultrasound examination, serum alpha-fetoprotein (AFP), Kleihauer-Betke test, and nonstress test (NST) were performed before and after the attempt at version. A version was not attempted if there was evidence of intrauterine growth retardation (IUGR), oligohydramnios, or a nonreactive NST. Patients in the tocolytic group received 200 micrograms/minute of ritodrine hydrochloride for 20 minutes via continuous intravenous infusion before a version was attempted. Twenty of the 30 patients (66.7%) in the tocolytic group and 19 of the 28 patients (67.8%) in the no-tocolytic group had successful versions, a nonsignificant difference. The nine patients with unsuccessful version attempts in the group without a tocolytic then received intravenous ritodrine and underwent a second attempt. Only one of these nine attempts was successful. There were no serious maternal or fetal complications associated with the attempts at version. In our patient population, use of a tocolytic did not significantly increase the probability of a successful version.

摘要

这项前瞻性研究评估了一种β-拟交感神经类宫缩抑制剂用于外倒转术的益处。从1984年7月1日至1987年5月15日,58例妊娠37 - 41周臀位的患者被纳入外倒转术评估。患者被随机分为两组:使用宫缩抑制剂组和不使用宫缩抑制剂组。在外倒转术前后均进行超声检查、血清甲胎蛋白(AFP)检测、改良Kleihauer - Betke试验及无应激试验(NST)。如果有宫内生长受限(IUGR)、羊水过少或无应激试验无反应的证据,则不尝试外倒转术。使用宫缩抑制剂组的患者在尝试外倒转术前通过持续静脉输注以每分钟200微克的速度给予盐酸利托君,持续20分钟。使用宫缩抑制剂组的30例患者中有20例(66.7%)外倒转术成功,未使用宫缩抑制剂组的28例患者中有19例(67.8%)成功,差异无统计学意义。未使用宫缩抑制剂组中9例外倒转术未成功的患者随后接受静脉注射利托君并进行第二次尝试。这9次尝试中仅1次成功。外倒转术尝试过程中未出现严重的母体或胎儿并发症。在我们的患者群体中,使用宫缩抑制剂并未显著增加外倒转术成功的概率。

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