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腹壁子宫内膜异位症合并透明细胞癌的手术治疗:病例报告及文献复习

Surgery of abdominal wall endometriosis associated with clear-cell carcinoma: Case report and review.

作者信息

Petit Clémence, Donval Lou, Chandeze Marie-Maëlle, Chis Carmen, Joste Marine, Panel Pierre

机构信息

Service de Gynécologie-Obstétrique, Centre hospitalier de Versailles - Hôpital André Mignot, 177 Rue de Versailles, 78150 Le Chesnay-Rocquencourt, France.

Service de Gynécologie-Obstétrique, Centre hospitalier de Versailles - Hôpital André Mignot, 177 Rue de Versailles, 78150 Le Chesnay-Rocquencourt, France.

出版信息

J Gynecol Obstet Hum Reprod. 2023 Apr;52(4):102561. doi: 10.1016/j.jogoh.2023.102561. Epub 2023 Feb 24.

Abstract

Abdominal wall is a rare location for endometriosis, with a reported incidence of parietal endometriosis of approximately 0.03 to 0.4%. It most often occurs in the aftermath of a caesarean section and is associated with pelvic endometriosis in only 5 to 15% of cases. Rare cases of malignant transformation have been described, mainly in the form of clear-cell tumours. We report the case of a 52-year-old patient with a history of endometriosis who presented with a retractile parietal mass at the level of her caesarean scar. Histological analysis confirmed a clear-cell adenocarcinoma (CCC). Few cases of endometriosis - associated CCC are described in the literature. A review of the literature suggests radical surgical treatment combined with adjuvant radio-chemotherapy. However, the prognosis is poor. The aim of this case report is to suggest the diagnosis of malignant transformation in the presence of a rapidly evolving parietal mass in the context of endometriosis and a history of caesarean section.

摘要

腹壁是子宫内膜异位症的罕见发病部位,据报道腹壁子宫内膜异位症的发病率约为0.03%至0.4%。它最常发生在剖宫产术后,仅5%至15%的病例与盆腔子宫内膜异位症相关。已有罕见的恶变病例报道,主要为透明细胞肿瘤形式。我们报告一例52岁有子宫内膜异位症病史的患者,其剖宫产瘢痕处出现一个可回缩的腹壁肿块。组织学分析证实为透明细胞腺癌(CCC)。文献中很少描述与子宫内膜异位症相关的CCC病例。文献综述提示采用根治性手术治疗并联合辅助放化疗。然而,预后较差。本病例报告的目的是提示在子宫内膜异位症及剖宫产病史背景下,出现快速进展的腹壁肿块时应考虑恶变的诊断。

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