外科性黄疸中恶性肿瘤及其类型的频率研究；一项三级护理经验。

The study of frequency of malignancy and its types in surgical jaundice; a tertiary care experience.

机构信息

Department of Surgery, King Edward Medical University, Mayo Hospital,Lahore, Pakistan.

出版信息

J Pak Med Assoc. 2023 Jan;73(1):9-12. doi: 10.47391/JPMA.3454.

DOI:10.47391/JPMA.3454

PMID:36841998

Abstract

OBJECTIVE

To determine the frequency of malignancy and its types in patients presenting with surgical jaundice in a tertiary care setting.

METHODS

The cross-sectional study was conducted at the North Surgical Ward, Mayo Hospital, Lahore, Pakistan, from May 8 to November 8, 2020, and comprised patients of either gender with a diagnosis of surgical jaundice made on the basis of history, clinical examination, haematological and biochemical reports and radiological investigations. All patients were managed as per the guidelines for surgical jaundice with injection vitamin K intramuscular, hydration with intravenous fluids, avoidance of constipation by lactulose or neomycin, vitals and urine output monitoring and prophylactic antibiotics. Demographic data as well frequency of malignancy were noted using a predesigned proforma. Data was analysed using SPSS 21.

RESULTS

Of the 95 patients, 51(53.7%) were male and 44(46.3%) were female. The overall mean age was 49.96±16.54 years (range: 18-80 years). A total of 19(20%) cases had body mass index <30. Malignancy was identified in 50(52.6%) cases; 14(28%) gallbladder, 4(8%) head of pancreas, 9(18%) peri-ampullary carcinoma, 7(14%) cholangiocarcinoma, 6(12%) Klastkin tumour, 5(10%) hepatocellular carcinoma, and 5(10%) metastatic tumour.

CONCLUSIONS

More than half of the surgical jaundice cases had malignancy, gallbladder being the most affected site.

摘要

目的

在三级医疗机构中确定以手术性黄疸就诊患者的恶性肿瘤发生率及其类型。

方法

本横断面研究于 2020 年 5 月 8 日至 11 月 8 日在巴基斯坦拉合尔的 Mayo 医院北外科病房进行，纳入的患者为基于病史、临床检查、血液学和生化报告以及影像学检查诊断为手术性黄疸的男女患者。所有患者均按照手术性黄疸指南进行治疗，包括肌内注射维生素 K、静脉补液、用乳果糖或新霉素预防便秘、监测生命体征和尿量以及预防性使用抗生素。使用预先设计的表格记录人口统计学数据和恶性肿瘤的发生频率。采用 SPSS 21 进行数据分析。

结果

95 例患者中，51 例（53.7%）为男性，44 例（46.3%）为女性。总体平均年龄为 49.96±16.54 岁（18-80 岁）。共有 19 例（20%）患者的体重指数<30。50 例（52.6%）患者确诊为恶性肿瘤；14 例（28%）为胆囊恶性肿瘤，4 例（8%）为胰头部恶性肿瘤，9 例（18%）为壶腹周围癌，7 例（14%）为胆管癌，6 例（12%）为 Klatskin 瘤，5 例（10%）为肝细胞癌，5 例（10%）为转移性肿瘤。