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一家三级眼科专科医院中儿童结构性角膜移植术的解剖学成功率。

Anatomical success of tectonic keratoplasty in children at a tertiary care eye hospital.

作者信息

Hassan Shadab, Noorani Sorath, Zaheer Naima, Jabeen Sidra

机构信息

Department of Pediatric Ophthalmology and Strabismus, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.

出版信息

J Pak Med Assoc. 2023 Jan;73(1):54-59. doi: 10.47391/JPMA.5532.

Abstract

OBJECTIVE

To evaluate the anatomical outcome of tectonic grafts performed in children with perforated or melted corneas.

METHODS

The prospective study was conducted at the Department of Paediatric Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from January to December 2017, and comprised children of either gender aged <16 years who received tectonic grafts owing to desmetocoele or corneal perforation of >3mm. The causes of corneal perforation, size of perforation, post-operative graft outcome and globe integrity were noted. Periodic follow-ups were done till December 2019. Data was analysed using SPSS 22.

RESULTS

Of the 27 patients, 9(33.3%) were girls and 18(66.7%) were boys. The overall mean age was 47.7±43.5 months. The most common indication was corneal perforation 19(70.4%), followed by descemetocoele 8(29.6%). The most frequent cause was infectious keratitis 13(48.2%), followed by trauma 8(29.6%) and vitamin A deficiency 5(18.5%). The mean size of perforation/descemetocoele was 5.5±1.5mm. Post-operatively, graft failure occurred in 5(18.5%) eyes and required repeat grafts. Globe integrity was restored in all 27(100%) cases, and 24(88.8%) eyes maintained their size and intraocular pressure, while 3(11.1%) became phthisical. Post-operative visual acuity was better than 6/36 in 3(11.1%) eyes, between 6/36 and 6/60 in 10(37%) and counting finger in 14(51.8%).

CONCLUSION

Tectonic graft was found to be a valuable therapeutic option in emergency globe-threatening corneal thinning and perforation and in maintaining the anatomical integrity of eyes.

摘要

目的

评估为角膜穿孔或融解患儿实施的结构性移植的解剖学结果。

方法

本前瞻性研究于2017年1月至12月在巴基斯坦拉瓦尔品第阿法信托眼科医院小儿眼科进行,纳入年龄<16岁因角膜后弹力层膨出或角膜穿孔>3mm而接受结构性移植的患儿。记录角膜穿孔的原因、穿孔大小、术后移植结果及眼球完整性。定期随访至2019年12月。使用SPSS 22对数据进行分析。

结果

27例患者中,女孩9例(33.3%),男孩18例(66.7%)。总体平均年龄为47.7±43.5个月。最常见的指征是角膜穿孔19例(70.4%),其次是角膜后弹力层膨出8例(29.6%)。最常见的病因是感染性角膜炎13例(48.2%),其次是外伤8例(29.6%)和维生素A缺乏5例(18.5%)。穿孔/角膜后弹力层膨出的平均大小为5.5±1.5mm。术后,5只眼(18.5%)发生移植失败,需要再次移植。所有27例(100%)病例的眼球完整性得以恢复,24只眼(88.8%)维持其大小和眼压,而3只眼(11.1%)萎缩。术后视力优于6/36的有3只眼(11.1%),介于6/36和6/60之间的有10只眼(37%),能数指的有14只眼(51.8%)。

结论

在紧急威胁眼球的角膜变薄和穿孔以及维持眼球解剖完整性方面,结构性移植是一种有价值的治疗选择。

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