Bartley G B, Bullock J D, Olsen T G, Lutz P D
Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905.
Ophthalmology. 1987 Oct;94(10):1286-9. doi: 10.1016/s0161-6420(87)80013-1.
Epilation, electrolysis, cryotherapy, and argon laser thermal ablation were used to remove eyelashes of rabbits. Epilation and electrolysis were done in the standard fashion. Nitrous oxide cryotherapy was applied in a double rapid-freeze/slow-thaw manner for either 30 or 60 seconds. Argon laser settings were 1 W, 50-micron spot size, and durations of 0.2, 0.5, or 1.0 second. The rabbits were euthanized immediately, 24 hours, 2 weeks, or 3 months after the procedure. Epilation was followed by total regrowth of eyelashes within 2 weeks. Electrolysis showed focal destruction of follicles with variable regrowth. Cryotherapy resulted in moderate-to-severe eyelid scarring with minimal regrowth. Argon laser thermal ablation produced focal necrosis and variable follicle destruction. Argon laser thermal ablation may be a suitable alternative to electrolysis or cryotherapy in selected cases of trichiasis.
采用拔毛术、电解法、冷冻疗法和氩激光热消融术去除兔睫毛。拔毛术和电解法按标准方式进行。一氧化二氮冷冻疗法以双重快速冷冻/缓慢解冻方式应用30秒或60秒。氩激光设置为1瓦、50微米光斑大小，持续时间为0.2、0.5或1.0秒。术后立即、24小时、2周或3个月对兔实施安乐死。拔毛术后2周内睫毛完全重新生长。电解法显示毛囊局灶性破坏，睫毛再生情况不一。冷冻疗法导致眼睑中度至重度瘢痕形成，睫毛再生极少。氩激光热消融造成局灶性坏死和毛囊破坏程度不一。在某些倒睫病例中，氩激光热消融可能是电解法或冷冻疗法的合适替代方法。
