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超声引导下经皮肋间冷冻神经lysis治疗CLOVES综合征慢性疼痛急性发作

Ultrasound-Guided Percutaneous Intercostal Cryoneurolysis for Acute-on-Chronic Pain in CLOVES Syndrome.

作者信息

Sen Sudipta, De Haan Johanna B, Mehrafza Mariam, Hernandez Nadia

机构信息

Anesthesiology and Perioperative Medicine, McGovern Medical School University of Texas Health Science Center, Houston, USA.

Anesthesiology, McGovern Medical School University of Texas Health Science Center, Houston, USA.

出版信息

Cureus. 2023 Jan 22;15(1):e34066. doi: 10.7759/cureus.34066. eCollection 2023 Jan.

DOI:10.7759/cureus.34066
PMID:36843754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9943689/
Abstract

Cryoneurolysis is an analgesic method that has been shown to provide extended pain relief in postoperative patients. However, to date, this method has not been described in nonsurgical inpatients with chronic pain experiencing an acute exacerbation. This analgesic modality has the potential to provide pain relief for patients whose expected duration of severe acute pain would outlast that of other regional anesthetic techniques while avoiding opioid escalation and facilitating discharge. We present a patient with acute exacerbation of chronic pain from breast ulcerations caused by congenital lipomatous overgrowth, vascular malformations, epidermal nevis, spinal/skeletal anomalies/scoliosis (CLOVES) syndrome that was successfully treated as an inpatient with a portable cryoneurolysis device.  This is the first reported use of cryoneurolysis in an inpatient setting to treat acute-on-chronic pain in a nonsurgical patient. The authors recommend regional anesthesiologists and acute pain specialists to utilize this technique to provide analgesia in patients with complex pain to facilitate hospital throughput.

摘要

冷冻神经lysis是一种镇痛方法,已被证明能为术后患者提供持久的疼痛缓解。然而,迄今为止,这种方法尚未在患有慢性疼痛急性加重的非手术住院患者中得到描述。这种镇痛方式有可能为那些预期严重急性疼痛持续时间超过其他区域麻醉技术的患者提供疼痛缓解,同时避免阿片类药物用量增加并促进出院。我们报告了一名因先天性脂肪瘤过度生长、血管畸形、表皮痣、脊柱/骨骼异常/脊柱侧凸(CLOVES)综合征导致乳腺溃疡引起慢性疼痛急性加重的患者,该患者作为住院患者使用便携式冷冻神经lysis设备成功得到治疗。这是首次报道在住院环境中使用冷冻神经lysis治疗非手术患者的慢性疼痛急性发作。作者建议区域麻醉医生和急性疼痛专家利用这种技术为复杂疼痛患者提供镇痛,以促进医院的工作效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2f9/9943689/4c192f1cfc42/cureus-0015-00000034066-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2f9/9943689/05abb54973a7/cureus-0015-00000034066-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2f9/9943689/4c192f1cfc42/cureus-0015-00000034066-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2f9/9943689/05abb54973a7/cureus-0015-00000034066-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2f9/9943689/4c192f1cfc42/cureus-0015-00000034066-i02.jpg

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Overgrowth syndromes, diagnosis and management.

本文引用的文献

1
Cryoanalgesia for postsurgical pain relief in adults: A systematic review and meta-analysis.成人术后疼痛缓解的冷冻镇痛:一项系统评价和荟萃分析。
Ann Med Surg (Lond). 2021 Aug 5;69:102689. doi: 10.1016/j.amsu.2021.102689. eCollection 2021 Sep.
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CLOVES syndrome: Treatment with oral Rapamycin. Report of two cases.CLOVES综合征:口服雷帕霉素治疗。两例报告。
Rev Chil Pediatr. 2019 Dec;90(6):662-667. doi: 10.32641/rchped.v90i6.1025.
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Interventional Cryoneurolysis: What Is the Same, What Is Different, What Is New?介入性冷冻神经溶解术:相同之处、不同之处、新进展?
过度生长综合征的诊断与治疗。
Curr Opin Pediatr. 2023 Dec 1;35(6):620-630. doi: 10.1097/MOP.0000000000001298. Epub 2023 Oct 4.
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Myonecrosis: A Rare Complication of Cryoneurolysis.肌坏死:冷冻神经溶解术的一种罕见并发症。
J Emerg Med. 2019 Sep;57(3):e73-e76. doi: 10.1016/j.jemermed.2019.06.017. Epub 2019 Aug 7.
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Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition).接受抗血栓或溶栓治疗患者的区域麻醉:美国区域麻醉和疼痛医学学会循证指南(第四版)
Reg Anesth Pain Med. 2018 Apr;43(3):263-309. doi: 10.1097/AAP.0000000000000763.
6
Ultrasound-guided percutaneous cryoneurolysis providing postoperative analgesia lasting many weeks following a single administration: a replacement for continuous peripheral nerve blocks?: a case report.超声引导下经皮冷冻神经溶解术单次给药后可提供持续数周的术后镇痛:能否替代连续外周神经阻滞?:一例病例报告
Korean J Anesthesiol. 2017 Oct;70(5):567-570. doi: 10.4097/kjae.2017.70.5.567. Epub 2017 Feb 3.
7
Pectoral Fascial (PECS) I and II Blocks as Rescue Analgesia in a Patient Undergoing Minimally Invasive Cardiac Surgery.胸肌筋膜(PECS)I 和 II 阻滞作为微创心脏手术患者的解救镇痛。
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Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves.用于治疗感觉和运动性周围神经的新型冷冻神经lysis装置。 (注:“lysis”常见释义为“分解、溶解” ,这里结合语境,可能是冷冻神经溶解之类的专业说法,但因专业领域可能有特定含义,整体译文可能需根据医学专业知识进一步优化。)
Expert Rev Med Devices. 2016 Aug;13(8):713-25. doi: 10.1080/17434440.2016.1204229. Epub 2016 Jul 13.