Akashi Yusuke, Horinishi Yuta, Sano Chiaki, Ohta Ryuichi
Family Medicine, Shimane University Medical School, Izumo, JPN.
Community Care, Unnan City Hospital, Unnan, JPN.
Cureus. 2023 Jan 24;15(1):e34154. doi: 10.7759/cureus.34154. eCollection 2023 Jan.
Idiopathic pulmonary fibrosis (IPF) is a group of diseases in which the main loci of lesions, mainly inflammatory and fibrotic, are within the interstitium of the alveolar and bronchiolar regions. Steroid therapy is the standard treatment for acute exacerbation of IPF, whereas antifibrotic agents are the standard treatment for chronic IPF. However, the vulnerability of older patients indicates that these treatments may be discontinued. Here, we report the case of an 86-year-old woman who had a dry cough for over a year and was subsequently diagnosed with IPF based on imaging studies. After using steroid pulses to treat acute exacerbations, the patient was transitioned to the chronic management phase, and time was allowed to plan the patient's advanced care with her family. The use of high-dose steroids in older patients with frailty is contraindicated. This case emphasizes the importance of considering initial intensive treatment for IPF in older patients for better palliative care.
特发性肺纤维化(IPF)是一组疾病,其主要病变部位(主要为炎症和纤维化)位于肺泡和细支气管区域的间质内。类固醇疗法是IPF急性加重期的标准治疗方法,而抗纤维化药物是慢性IPF的标准治疗方法。然而,老年患者的脆弱性表明这些治疗可能需要中断。在此,我们报告一例86岁女性病例,该患者干咳超过一年,随后根据影像学检查被诊断为IPF。在使用类固醇冲击疗法治疗急性加重期后,患者进入慢性管理阶段,并留出时间与家人一起规划患者的晚期护理。老年体弱患者禁忌使用高剂量类固醇。该病例强调了考虑对老年IPF患者进行初始强化治疗以实现更好姑息治疗的重要性。