Verplaetse Terril L, Roberts Walter, Peltier MacKenzie R, Zakiniaeiz Yasmin, Burke Catherine, Moore Kelly E, Pittman Brian, McKee Sherry A
Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Psychology Service, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
Drug Alcohol Depend Rep. 2021 Nov 26;1:100007. doi: 10.1016/j.dadr.2021.100007. eCollection 2021 Dec.
Heavy alcohol use is associated with increased risk of alcohol-related health consequences. Alcohol consumption has increased in females in the last fifteen years and females are more likely to experience exacerbated health risks due to drinking. Our group identified that females with AUD were more likely to report respiratory conditions or cancers compared to their male counterparts. This analysis sought to further examine relationships between sex and alcohol use on medical conditions by using the new 2020 U.S. Dietary Guidelines risk drinking levels.
Data from the U.S. National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III; = 36,309) was used to evaluate associations between sex (female vs. male) and alcohol risk drinking levels (abstainer, binge, heavy, extreme binge vs. moderate drinking) on past year self-reported doctor-confirmed medical conditions).
Females were 1.5 to 2 times more likely to have pain, respiratory, or other medical conditions in the past year (odds ratio []=1.46-2.11) vs. males. Significant interactions demonstrated that heavy drinking females or extreme binge drinking females were 2 to 3 times more likely to have cancers or other conditions (=1.95-2.69) vs. males at the same risk drinking level. Female abstainers were more likely than male abstainers to have other medical conditions (=1.77).
Consistent with our previous findings, results identify that higher risk drinking levels are associated with the presence of past year self-reported doctor-confirmed medical conditions spanning organ systems, particularly in females. Treatment for high-risk drinking should be considered in the clinical care of individuals with significant medical conditions.
大量饮酒与酒精相关健康后果风险增加有关。在过去十五年中，女性饮酒量有所增加，并且女性因饮酒更易出现加剧的健康风险。我们的研究小组发现，与男性相比，患有酒精使用障碍（AUD）的女性更有可能报告呼吸系统疾病或癌症。本分析旨在通过使用新的2020年美国膳食指南中的风险饮酒水平，进一步研究性别与饮酒对医疗状况的关系。
使用来自美国国家酒精及相关状况流行病学调查（NESARC-III；n = 36,309）的数据，评估性别（女性与男性）与过去一年自我报告的经医生确认的医疗状况下的酒精风险饮酒水平（戒酒者、暴饮者、重度饮酒者、极端暴饮者与适度饮酒者）之间的关联。
与男性相比，女性在过去一年中出现疼痛、呼吸系统或其他医疗状况的可能性高1.5至2倍（优势比[OR]=1.46 - 2.11）。显著的交互作用表明，在相同的风险饮酒水平下，重度饮酒女性或极端暴饮女性患癌症或其他疾病的可能性比男性高2至3倍（OR = 1.95 - 2.69）。女性戒酒者比男性戒酒者更易出现其他医疗状况（OR = 1.77）。
与我们之前的研究结果一致，本研究结果表明，较高的风险饮酒水平与过去一年自我报告的经医生确认的涉及多个器官系统的医疗状况有关，尤其是在女性中。对于患有严重医疗状况的个体，临床护理中应考虑对高危饮酒进行治疗。
