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First-line therapy in drug reaction with eosinophilia and systemic symptoms (DReSS): Thinking beyond corticosteroids.药物超敏反应伴嗜酸性粒细胞增多和全身症状（DReSS）的一线治疗：超越皮质类固醇的思考。
Front Med (Lausanne). 2023 Feb 8;10:1138464. doi: 10.3389/fmed.2023.1138464. eCollection 2023.
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Vancomycin Drug Reaction with Eosinophilia and Systemic Symptoms: Meta-Analysis and Pharmacovigilance Study.万古霉素所致嗜酸粒细胞增多和全身症状药物反应：荟萃分析与药物警戒研究
J Clin Med. 2025 Jan 31;14(3):930. doi: 10.3390/jcm14030930.
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Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments.解读成人红皮病的病因：临床表现、诊断工具、病理生理学和治疗方法的最新指南。
Am J Clin Dermatol. 2024 Nov;25(6):927-950. doi: 10.1007/s40257-024-00886-9. Epub 2024 Sep 30.
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DRESS and Stevens-Johnson Syndrome Overlap Secondary to Allopurinol in a 50-Year-Old Man-A Diagnostic and Treatment Challenge: Case Report.一名50岁男性因别嘌醇继发的中毒性表皮坏死松解症与史蒂文斯-约翰逊综合征重叠——诊断与治疗挑战：病例报告
Life (Basel). 2023 Nov 24;13(12):2251. doi: 10.3390/life13122251.
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Renal Manifestations of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Systematic Review of 71 Cases.药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）综合征的肾脏表现：71例病例的系统评价
J Clin Med. 2023 Jul 10;12(14):4576. doi: 10.3390/jcm12144576.

本文引用的文献

1
Drug-Induced Hypersensitivity Syndrome (DIHS)/Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis.药物诱导的超敏反应综合征（DIHS）/伴嗜酸性粒细胞增多和全身症状的药物反应（DRESS）：临床特征和发病机制。
J Allergy Clin Immunol Pract. 2022 May;10(5):1155-1167.e5. doi: 10.1016/j.jaip.2022.02.004. Epub 2022 Feb 15.
2
Successful treatment of corticosteroid-dependent drug reaction with eosinophilia and systemic symptoms with cyclosporine.环孢素成功治疗依赖皮质类固醇的药物反应伴嗜酸性粒细胞增多和全身症状。
Ann Allergy Asthma Immunol. 2021 Dec;127(6):674-681. doi: 10.1016/j.anai.2021.08.012. Epub 2021 Aug 13.
3
Reporting of drug reaction with eosinophilia and systemic symptoms from 2002 to 2019 in the US Food and Drug Administration Adverse Event Reporting System.2002年至2019年美国食品药品监督管理局不良事件报告系统中嗜酸性粒细胞增多和全身症状药物反应的报告
J Allergy Clin Immunol Pract. 2021 Aug;9(8):3208-3211.e1. doi: 10.1016/j.jaip.2021.05.008. Epub 2021 May 24.
4
Evaluation of Cyclosporine for the Treatment of DRESS Syndrome.环孢素治疗药物超敏反应综合征的评价。
JAMA Dermatol. 2020 Jun 1;156(6):704-706. doi: 10.1001/jamadermatol.2020.0048.
5
Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report.基于单细胞转录组分析的靶向治疗在药物诱导的超敏反应综合征中的应用：一例报告。
Nat Med. 2020 Feb;26(2):236-243. doi: 10.1038/s41591-019-0733-7. Epub 2020 Jan 20.
6
Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms severity score: A useful tool for assessing disease severity and predicting fatal cytomegalovirus disease.药物诱导的超敏反应/伴有嗜酸性粒细胞增多和全身症状的药物反应严重程度评分：评估疾病严重程度和预测致命性巨细胞病毒病的有用工具。
J Am Acad Dermatol. 2019 Mar;80(3):670-678.e2. doi: 10.1016/j.jaad.2018.08.052. Epub 2018 Sep 18.
7
DRESS syndrome: Part II. Management and therapeutics.药物反应伴嗜酸性粒细胞增多和全身性症状（DRESS）综合征：第二部分。管理与治疗。
J Am Acad Dermatol. 2013 May;68(5):709.e1-9; quiz 718-20. doi: 10.1016/j.jaad.2013.01.032.

First-line therapy in drug reaction with eosinophilia and systemic symptoms (DReSS): Thinking beyond corticosteroids.

作者信息

Verstegen Ruud H J, Phillips Elizabeth J, Juurlink David N

机构信息

Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

Division of Clinical Pharmacology and Toxicology, Department of Paediatrics, The Hospital for Sick Children, Toronto, ON, Canada.

出版信息

Front Med (Lausanne). 2023 Feb 8;10:1138464. doi: 10.3389/fmed.2023.1138464. eCollection 2023.

DOI:10.3389/fmed.2023.1138464
PMID:36844223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9944398/
Abstract
摘要