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用于大面积剥脱性骨软骨炎病变的MACI“三明治”技术：一例报告

MACI "Sandwich" Technique for a Large Osteochondritis Dissecans Lesion: A Case Report.

作者信息

Desai Bhumit, Jacobs Graylin, Jones Deryk

机构信息

Department of Orthopaedic Surgery, Ochsner Medical Center, 1514 Jefferson Hwy, Jefferson, LA 70121, USA.

Ochsner Sports Medicine Institute, 1201 S. Clearview Pkwy, New Orleans, LA 70121, USA.

出版信息

Case Rep Orthop. 2023 Feb 15;2023:7612206. doi: 10.1155/2023/7612206. eCollection 2023.

DOI:10.1155/2023/7612206
PMID:36844705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9946755/
Abstract

There is widespread use of matrix-induced autologous chondrocyte implantation. Initial use of autologous bone grafting in combination with the matrix-induced autologous chondrocyte implantation procedure has shown efficacy in small- to medium-sized osteochondral lesions. This case report demonstrates use of the "Sandwich" technique in a large, deep osteochondritis dissecans lesion of the medial femoral condyle. Technical considerations that are key to containment of the lesion and outcomes are reported.

摘要

基质诱导自体软骨细胞植入术已得到广泛应用。最初将自体骨移植与基质诱导自体软骨细胞植入术联合使用，已证明对中小尺寸的骨软骨损伤有效。本病例报告展示了“三明治”技术在股骨内侧髁大型、深度剥脱性骨软骨炎损伤中的应用。报告了对损伤的控制及结果起关键作用的技术要点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed8a/9946755/f1bdfee1c5aa/CRIOR2023-7612206.016.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed8a/9946755/c8cf9f28de61/CRIOR2023-7612206.001.jpg
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Br Med Bull. 2021 Dec 16;140(1):50-61. doi: 10.1093/bmb/ldab024.
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Autologous Chondrocyte Implantation "Segmental-Sandwich" Technique for Deep Osteochondral Defects in the Knee: Clinical Outcomes and Correlation With Magnetic Resonance Imaging Findings.自体软骨细胞移植“节段三明治”技术治疗膝关节深层骨软骨缺损：临床结果及与磁共振成像结果的相关性
Orthop J Sports Med. 2019 May 28;7(5):2325967119847173. doi: 10.1177/2325967119847173. eCollection 2019 May.
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Matrix-Induced Autologous Chondrocyte Implantation With Autologous Bone Grafting for Osteochondral Lesions of the Femoral Trochlea.
基质诱导自体软骨细胞植入联合自体骨移植治疗股骨滑车骨软骨损伤
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Osteochondral lesion depth on MRI can help predict the need for a sandwich procedure.MRI上的骨软骨损伤深度有助于预测是否需要进行三明治手术。
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