儿童胰岛素抵抗的可靠评估
Reliable Assessment of Insulin Resistance in Children.
作者信息
Van Name Michelle, Caprio Sonia
机构信息
Department of Pediatrics, Yale University School of Medicine, New Haven, CT.
出版信息
Curr Cardiovasc Risk Rep. 2013 Aug;7(4):256-260. doi: 10.1007/s12170-013-0315-z. Epub 2013 Jun 5.
Abstract
Obesity is on the rise in the pediatric population. Obese individuals are at risk for insulin resistance, and this in combination with impaired β-cell function can result in type 2 diabetes. The diagnosis of insulin resistance is made in clinical practice by using estimates of insulin sensitivity. Scientific evidence regarding the evaluation of insulin resistance in children has revealed conflicting conclusions.
摘要
肥胖在儿童群体中呈上升趋势。肥胖个体存在胰岛素抵抗风险，而这与β细胞功能受损相结合可能导致2型糖尿病。在临床实践中，通过胰岛素敏感性评估来诊断胰岛素抵抗。关于儿童胰岛素抵抗评估的科学证据得出了相互矛盾的结论。
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