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加纳阿克拉科勒布教学医院腐蚀性咽食管损伤的处理:29 例回顾性研究

Management of caustic pharyngoesophageal injuries in Korle Bu Teaching Hospital, Accra, Ghana: a 12-year retrospective review of 29 cases.

机构信息

University of Ghana Medical School, University of Ghana, Accra, Ghana.

National Cardiothoracic Centre, Korle Bu Teaching Hospital, Accra, Ghana.

出版信息

Pan Afr Med J. 2022 Jul 19;42:213. doi: 10.11604/pamj.2022.42.213.30206. eCollection 2022.

Abstract

INTRODUCTION

caustic pharyngoesophageal strictures are life-threatening injuries with important management difficulties, lacking clear therapeutic guidelines. The aim of this study is to evaluate the surgical procedures and outcomes of severe caustic pharyngoesophageal strictures in our institution.

METHODS

a total of 29 patients who underwent surgery for severe caustic pharyngoesophageal injury at the National Cardiothoracic Center from June 2006 to December 2018 were retrospectively reviewed. The age distribution, sex, management procedures, complications after surgery, and the outcome were analyzed.

RESULTS

there were 17 males. The mean age was 11.7 years (range 2- 56 years). All patients accidentally swallowed caustic soda, except the oldest patient who ingested an unidentified substance. The treatment procedures included colopharyngoplasty in 15 (51.7%) patients, colon-flap augmentation pharyngoesophagoplasty (CFAP) in 10 (34.5%), and colopharyngoplasty with tracheostomy in 4 (13.8%). There was one case of graft obstruction from a retrosternal adhesive band and one case of postoperative reflux with nocturnal regurgitation. No cervical anastomotic leak occurred. Rehabilitative training for oral feeding was required for less than a month in most patients. Follow-up period ranged from one to twelve years. Four patients died within this period; two were immediate post-operative deaths and two occurred late. One patient was lost to follow-up.

CONCLUSION

outcome of surgery for caustic pharyngoesophageal stricture is satisfactory. Colon-flap augmentation pharyngoesophagoplasty reduces the need for tracheostomy before surgery, and our patients start eating early without aspiration.

摘要

介绍

腐蚀性咽食管狭窄是一种危及生命的损伤,具有重要的治疗困难,缺乏明确的治疗指南。本研究旨在评估本中心严重腐蚀性咽食管狭窄的手术治疗效果。

方法

回顾性分析 2006 年 6 月至 2018 年 12 月在国家心胸中心因严重腐蚀性咽食管损伤接受手术的 29 例患者。分析患者的年龄分布、性别、治疗方法、术后并发症及治疗效果。

结果

患者均为男性,年龄 2-56 岁,平均 11.7 岁,均为意外吞食强碱,仅 1 例为 60 岁老人,吞食不明物质。治疗方法包括咽成形术 15 例(51.7%)、结肠瓣咽食管重建术 10 例(34.5%)和结肠瓣咽成形术加气管造口术 4 例(13.8%)。术后发生吻合口狭窄 1 例,胸骨后粘连带导致移植皮瓣阻塞 1 例,发生反流 1 例。无颈部吻合口瘘。大多数患者术后 1 个月内开始经口进食,康复训练。随访 1-12 年,4 例患者死亡,其中 2 例为术后早期死亡,2 例为晚期死亡,1 例失访。

结论

手术治疗腐蚀性咽食管狭窄效果满意。结肠瓣咽食管重建术可减少术前气管造口的需要,患者术后早期开始经口进食,无吸入。

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