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间变性甲状腺癌胰腺转移:1例罕见病例报告

A pancreatic metastasis of anaplastic thyroid carcinoma: a rare case report.

作者信息

Zarg El Ayoun Radhwen, Chtourou Mohamed F, Beji Hazem, Kchaou Majdi, Belfekih Houda, Chelbi Emna, Mighri Mohamed M, Touinsi Hassen

机构信息

Department of general surgery, Hospital Mohamed Taher Maamouri, Nabeul.

Faculty of Medicine of Tunis, University of Tunis El Manar.

出版信息

Ann Med Surg (Lond). 2023 Feb 7;85(2):228-230. doi: 10.1097/MS9.0000000000000179. eCollection 2023 Feb.

Abstract

UNLABELLED

Anaplastic thyroid carcinoma (ATC) is a rare malignancy with a poor prognosis. It is characterized by abrupt development with local and distant metastases. Metastases are essentially present in the lung. Pancreatic metastasis is extremely rare. The authors report that, to their knowledge, this is the first reported case of a patient who developed metachronous pancreatic metastasis related to ATC.

CASE PRESENTATION

A 65-year-old woman, with a history of thyroidectomy, 2 years prior, for an anaplastic thyroid tumor presented in his regular follow-up computed tomography scan a hypodense lesion of the head of the pancreas. Definite diagnosis of neoplasm was difficult following the computed tomography-guided fine-needle aspiration biopsy. The patient had a cephalic duodenopanceatectomy with an uneventful recovery. Histopathology concluded in a pancreatic metastasis of ATC metastasis. The patient had uneventful outcomes with a follow-up of 3 months without tumor recurrence.

CONCLUSION

Pancreatic metastases of thyroid carcinomas are extremely rare, particularly for ATC. The diagnosis of metastases is based on a regular follow-up. The prognosis is poor despite curative surgery.

摘要

摘要

未分化甲状腺癌(ATC)是一种罕见的恶性肿瘤,预后较差。其特点是发展迅速,伴有局部和远处转移。转移主要发生在肺部。胰腺转移极为罕见。作者报告,据他们所知,这是首例报道的与ATC相关的异时性胰腺转移患者。

病例介绍

一名65岁女性,2年前因未分化甲状腺肿瘤接受了甲状腺切除术,在其定期随访的计算机断层扫描中,胰腺头部出现一个低密度病变。在计算机断层扫描引导下进行细针穿刺活检后,难以明确肿瘤诊断。患者接受了胰十二指肠切除术,恢复顺利。组织病理学结果为ATC胰腺转移。患者随访3个月,无肿瘤复发,预后良好。

结论

甲状腺癌的胰腺转移极为罕见,尤其是ATC。转移的诊断基于定期随访。尽管进行了根治性手术,预后仍较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/426b/9949859/f6a4685f4fda/ms9-85-228-g001.jpg

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