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124I-PET/CT 引导下胰腺转移甲状腺乳头状癌的诊断及个体化治疗

124I-PET/CT-Guided Diagnosis and Personalized Treatment of Metastatic Papillary Thyroid Cancer to the Pancreas.

机构信息

From the Department of Medical Imaging, Gold Coast University Hospital, Southport.

Department of Nuclear Medicine & Specialised PET Services, Royal Brisbane & Women's Hospital, Brisbane, Australia.

出版信息

Clin Nucl Med. 2021 Apr 1;46(4):337-339. doi: 10.1097/RLU.0000000000003499.

DOI:10.1097/RLU.0000000000003499
PMID:33492854
Abstract

Metastasis to the pancreas from differentiated thyroid carcinoma is rare. A new pancreatic lesion was identified on surveillance imaging of a man with metastatic papillary thyroid carcinoma 7 years after initial diagnosis. Imaging with 124I-PET/CT was performed to noninvasively confirm metastatic thyroid cancer and provide prospective dosimetry to guide selection of a safe and effective administered activity of 131I. This case demonstrates the emerging role of 124I-PET/CT as a useful diagnostic scan, pretherapy scan, and dosimetric tool to deliver personalized therapy for patients with metastatic thyroid cancer.

摘要

甲状腺癌转移至胰腺较为罕见。一名男性患者在初始诊断 7 年后的随访影像学检查中发现新的胰腺病灶,该患者患有甲状腺乳头状癌伴转移。为了非侵入性地确认转移性甲状腺癌并提供前瞻性剂量测定以指导选择安全有效的 131I 给药剂量,对其进行了 124I-PET/CT 检查。该病例表明 124I-PET/CT 作为一种有用的诊断性扫描、治疗前扫描和剂量测定工具,可为转移性甲状腺癌患者提供个性化治疗。

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