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口服维甲酸衍生物治疗银屑病

[Treatment of psoriasis with a derivative of retinoic acid by oral route].

作者信息

Viglioglia P, Barclay C A

出版信息

Med Cutan Ibero Lat Am. 1977;5(6):433-42.

PMID:368464
Abstract

In the study presented, an evaluation has been made of the results achieved in a group of 32 psoriatic patients treated with a derivative of the retinoid acid, i.e. Ro 10-9359, taken orally. The therapy used was considered highly favourable in 28 cases and favourable in 3. It is considered that the treatment is effective independently of the time of evolution and of the extension of seriousness of the disease with no effects on the visceral or humoral sectors. All the information included in the present study allows to assert that the treatment of psoriasis with this derivative of the retinoid acid represents a significant progress as compared with the corticoids or cythostatics therapy.

摘要

在本研究中,对一组32名口服维甲酸衍生物Ro 10-9359治疗的银屑病患者的治疗结果进行了评估。所采用的治疗方法在28例患者中被认为非常有效,3例患者效果良好。该治疗被认为无论疾病进展时间和严重程度如何均有效,且对内脏或体液系统无影响。本研究中的所有信息表明,与皮质类固醇或细胞抑制剂疗法相比,用这种维甲酸衍生物治疗银屑病代表了显著的进步。

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