Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA.
Crit Care Med. 2023 May 1;51(5):584-593. doi: 10.1097/CCM.0000000000005822. Epub 2023 Feb 28.
To examine 1-year functional outcomes after invasive mechanical ventilation for adults greater than or equal to 65 years with preexisting long-term care-needs.
We used medical and long-term care administrative databases. The database included data on functional and cognitive impairments that were assessed with the national standardized care-needs certification system and were categorized into seven care-needs levels based on the total daily estimated care minutes. Primary outcome was mortality and care-needs at 1 year after invasive mechanical ventilation. Outcome was stratified by preexisting care-needs at the time of invasive mechanical ventilation: no care-needs, support level 1-2 and care-needs level 1 (estimated care time 25-49 min), care-needs level 2-3 (50-89 min), and care-needs level 4-5 (≥90 min).
A population-based cohort study in Tochigi Prefecture, one of 47 prefectures in Japan.
Among people greater than or equal to 65 years old registered between June 2014 and February 2018, patients who received invasive mechanical ventilation were identified.
None.
Among 593,990 eligible people, 4,198 (0.7%) received invasive mechanical ventilation. The mean age was 81.2 years, and 55.5% were male. The 1-year mortality rates after invasive mechanical ventilation in patients with no care-needs, support level 1-2 and care-needs level 1, care-needs level 2-3, and care-needs level 4-5 at the time of invasive mechanical ventilation were 43.4%, 54.9%, 67.8%, and 74.1%, respectively. Similarly, those with worsened care-needs were 22.8%, 24.2%, 11.4%, and 1.9%, respectively.
Among patients in preexisting care-needs levels 2-5 who received invasive mechanical ventilation, 76.0-79.2% died or had worsened care-needs within 1 year. These findings may aid shared decision-making among patients, their families, and heath care professionals on the appropriateness of starting invasive mechanical ventilation for people with poor functional and cognitive status at baseline.
研究患有长期护理需求的≥65 岁成人接受有创机械通气治疗 1 年后的功能预后。
我们使用医疗和长期护理管理数据库。该数据库包含功能和认知障碍的数据,这些数据是通过国家标准化护理需求认证系统评估的,并根据每日估计护理时间分为七个护理需求级别。主要结局是有创机械通气治疗 1 年后的死亡率和护理需求。根据有创机械通气时的预先存在的护理需求进行分层:无护理需求、支持级别 1-2 和护理需求级别 1(估计护理时间 25-49 分钟)、护理需求级别 2-3(50-89 分钟)和护理需求级别 4-5(≥90 分钟)。
本研究是在日本 47 个都道府县之一的栃木县进行的基于人群的队列研究。
在 2014 年 6 月至 2018 年 2 月期间登记的≥65 岁人群中,确定接受有创机械通气的患者。
无。
在 593990 名合格人群中,有 4198 人(0.7%)接受了有创机械通气。患者的平均年龄为 81.2 岁,其中 55.5%为男性。无护理需求、支持级别 1-2 和护理需求级别 1、护理需求级别 2-3 和护理需求级别 4-5 的患者在接受有创机械通气后 1 年的死亡率分别为 43.4%、54.9%、67.8%和 74.1%。同样,护理需求恶化的患者分别为 22.8%、24.2%、11.4%和 1.9%。
在预先存在的 2-5 级护理需求的患者中,有 76.0-79.2%的患者在 1 年内死亡或护理需求恶化。这些发现可能有助于患者、他们的家人和卫生保健专业人员就基线功能和认知状态较差的人开始有创机械通气的适当性做出共同决策。