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Intratumoral and Microenvironmental Heterogeneity in Patient Outcome Prediction.

作者信息

Beckman Robert A, Makohon-Moore Alvin P, Puzanov Igor

机构信息

Departments of Oncology and of Biostatistics, Bioinformatics, and Biomathematics, Lombardi Comprehensive Cancer Center and Innovation Center for Biomedical Informatics, Georgetown University Medical Center, Washington, DC.

Hackensack Meridian Health Center for Discovery and Innovation, Nutley, NJ.

出版信息

JCO Precis Oncol. 2023 Feb;7:e2200698. doi: 10.1200/PO.22.00698.

DOI:10.1200/PO.22.00698
PMID:36848610
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10309571/
Abstract
摘要

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引用本文的文献

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Reply to M. Younes.回复尤尼斯先生。
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Assessing the Increased Variability in Individual Lesion Kinetics During Immunotherapy: Does It Exist, and Does It Matter?评估免疫治疗期间个体病灶动力学增加的变异性:它是否存在,以及是否重要?
JCO Precis Oncol. 2023 Feb;7:e2200368. doi: 10.1200/PO.22.00368.
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How Should Cancer Models Be Constructed?癌症模型应该如何构建?
Cancer Control. 2020 Jan-Dec;27(1):1073274820962008. doi: 10.1177/1073274820962008.
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Rare Mutations in Cancer Drug Resistance and Implications for Therapy.癌症耐药中的罕见突变及其对治疗的影响
Clin Pharmacol Ther. 2020 Sep;108(3):437-439. doi: 10.1002/cpt.1938. Epub 2020 Jul 10.
4
The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies.肿瘤微环境对免疫检查点阻断治疗的反应。
Front Immunol. 2020 May 7;11:784. doi: 10.3389/fimmu.2020.00784. eCollection 2020.
5
Tumor circulome in the liquid biopsies for cancer diagnosis and prognosis.液体活检中的肿瘤循环组学用于癌症的诊断和预后。
Theranostics. 2020 Mar 15;10(10):4544-4556. doi: 10.7150/thno.40532. eCollection 2020.
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Extensive subclonal mutational diversity in human colorectal cancer and its significance.人类结直肠癌中广泛的亚克隆突变多样性及其意义。
Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26863-26872. doi: 10.1073/pnas.1910301116. Epub 2019 Dec 5.
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An analysis of genetic heterogeneity in untreated cancers.未治疗癌症中的遗传异质性分析。
Nat Rev Cancer. 2019 Nov;19(11):639-650. doi: 10.1038/s41568-019-0185-x. Epub 2019 Aug 27.
8
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer.胰腺癌个体患者转移灶中已知驱动基因突变的异质性有限。
Nat Genet. 2017 Mar;49(3):358-366. doi: 10.1038/ng.3764. Epub 2017 Jan 16.
9
Comparison of CT volumetric measurement with RECIST response in patients with lung cancer.肺癌患者CT容积测量与RECIST反应的比较。
Eur J Radiol. 2016 Mar;85(3):524-33. doi: 10.1016/j.ejrad.2015.12.019. Epub 2016 Jan 2.
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The influence of subclonal resistance mutations on targeted cancer therapy.亚克隆耐药突变对靶向癌症治疗的影响。
Nat Rev Clin Oncol. 2016 Jun;13(6):335-47. doi: 10.1038/nrclinonc.2015.175. Epub 2015 Oct 20.