Kotnik Tina
Small Animal Clinic, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Vet Sci. 2023 Jan 18;10(2):72. doi: 10.3390/vetsci10020072.
The quality of life (QoL) of dogs with canine atopic dermatitis (CAD) treated with allergen-specific immunotherapy (ASIT) was studied to determine whether the QoL of dogs treated with ASIT (AG) improved compared with dogs not treated with ASIT (CG).
The power of the study was calculated in advance assuming that the AG would assess QoL 20% better than the CG. The CG consisted of 21 dogs with CAD and the AG of 46 dogs with CAD. Validated QoL1 (pre-treatment) and QoL2 (post-treatment) questionnaires were emailed to owners.
AG dogs were significantly less disturbed during mealtimes (i.e., had better appetites and scratched less during mealtimes) and caused significantly less physical discomfort to their owners (due to unpleasant odor, the impression of a dirty apartment) than CG dogs. Owners of dogs treated with ASIT were able to significantly improve their daily activities (leisure, vacation, walks, work, hunting), significantly reduce their expenses (treatment costs, veterinary costs), feel significantly less emotional distress (less guilt, powerlessness, sadness, regret, fear, anger, disgust, rage, frustration), and experience less influence on relationships with family members and friends compared to owners of dogs not treated with ASIT.
According to our results, the quality of life of dogs treated with ASIT and their owners seemed to improve significantly.
对接受变应原特异性免疫疗法（ASIT）治疗的犬异位性皮炎（CAD）犬的生活质量（QoL）进行了研究，以确定接受ASIT治疗的犬（AG组）与未接受ASIT治疗的犬（CG组）相比，其生活质量是否得到改善。
预先计算研究效能，假设AG组犬的生活质量评估比CG组犬好20%。CG组由21只患有CAD的犬组成，AG组由46只患有CAD的犬组成。将经过验证的QoL1（治疗前）和QoL2（治疗后）问卷通过电子邮件发送给犬主。
与CG组犬相比，AG组犬在用餐时受到的干扰明显更少（即食欲更好，用餐时抓挠更少），给犬主带来的身体不适也明显更少（由于难闻的气味、公寓脏乱的印象）。与未接受ASIT治疗的犬的犬主相比，接受ASIT治疗的犬的犬主能够显著改善他们的日常活动（休闲、度假、散步、工作、狩猎），显著减少开支（治疗费用、兽医费用），感到的情绪困扰明显更少（更少的内疚、无力感、悲伤、遗憾、恐惧、愤怒、厌恶、暴怒、沮丧），并且在与家人和朋友的关系上受到的影响也更小。
根据我们的结果，接受ASIT治疗的犬及其犬主的生活质量似乎有显著改善。
