Goldrich Alisa, Yuan Jessica, Stohl Hindi
Harbor-UCLA Medical Center, Department of Obstetrics and Gynecology, 1000 West Carson Street, Torrance, CA 90502, USA.
Case Rep Womens Health. 2023 Feb 14;37:e00487. doi: 10.1016/j.crwh.2023.e00487. eCollection 2023 Mar.
Gestational diabetes insipidus (GDI) is a rare complication of pregnancy thought to be due to increased vasopressinase produced by the placenta. It typically occurs at the end of the second or in the third trimester. This report describes a case of GDI diagnosed postpartum in the setting of newly diagnosed superimposed preeclampsia. A 39-year-old Hispanic woman (gravida 2 para 2) presented ten days postpartum with a persistent headache and elevated blood pressures in the setting of a history of chronic hypertension, meeting criteria for superimposed preeclampsia. Repeat lab work was notable for mild elevation of liver function enzymes. Despite normalization of blood pressures, her headache persisted and further workup revealed polyuria, suspected to be vasopressinase-induced diabetes insipidus. The patient was started on oral desmopressin with improvement of polyuria and symptoms.
妊娠性尿崩症（GDI）是一种罕见的妊娠并发症，被认为是由于胎盘产生的血管加压素酶增加所致。它通常发生在妊娠晚期的第二个月末或第三个月。本报告描述了一例产后诊断为GDI的病例，该病例同时伴有新诊断的叠加性先兆子痫。一名39岁的西班牙裔女性（孕2产2）产后10天出现持续性头痛和血压升高，有慢性高血压病史，符合叠加性先兆子痫的标准。复查实验室检查发现肝功能酶轻度升高。尽管血压恢复正常，但她的头痛仍持续存在，进一步检查发现多尿，怀疑是血管加压素酶诱导的尿崩症。患者开始口服去氨加压素后，多尿及症状有所改善。
