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头颈部癌症放疗患者中牙种植体的疗效:伞式综述。

Effectiveness of dental implants in patients undergoing radiotherapy for head and neck cancer: An umbrella review.

机构信息

Department of Prosthesis and Oral and Maxillofacial Surgery, Dental School, Federal University of Pernambuco, Recife, Brazil.

Real Hospital Português, Recife, Brazil.

出版信息

Spec Care Dentist. 2024 Jan-Feb;44(1):40-56. doi: 10.1111/scd.12840. Epub 2023 Feb 28.

DOI:10.1111/scd.12840
PMID:36852979
Abstract

OBJECTIVE

The objective of this overview is to evaluate the effectiveness of dental implants placed in patients who underwent radiotherapy for the treatment of head and neck cancer, as well as to assess the methodological quality of the included systematic reviews.

METHODS

The study was conducted in four PubMed, Lilacs, Dare Cochrane and Google Scholar databases until July 2022, using the descriptors "Radiotherapy," "Dental implants," and "Head and Neck Cancer."

RESULTS

958 studies were found in the initial search and after applying the inclusion and exclusion criteria, fifteen systematic reviews were selected to compose this overview and had their methodological quality evaluated by the AMSTAR 2 tool.

RESULTS

24,996 implants in 5487 patients were evaluated with a rate of success rate of 86.2% in patients who underwent radiotherapy and 95.2% in patients who did not undergo radiotherapy. Only one of the systematic reviews was of high quality according to AMSTAR 2.

CONCLUSION

Oral rehabilitation with dental implants in patients with a history of head and neck cancer undergoing radiotherapy is a valid therapy. However, given the level of evidence found, further studies with better design are necessary to provide greater confidence in the clinical decision.

摘要

目的

本次综述的目的是评估头颈部癌症放疗患者中植入的牙种植体的有效性,并评估纳入的系统评价的方法学质量。

方法

本研究于 2022 年 7 月前在四个 PubMed、Lilacs、Cochrane 的 Dare 和 Google Scholar 数据库中进行,使用的检索词为“放射疗法”、“牙种植体”和“头颈部癌症”。

结果

初步检索共发现 958 项研究,经过纳入和排除标准后,选择了 15 项系统评价来组成本次综述,并使用 AMSTAR 2 工具评估其方法学质量。

结果

共评估了 5487 例患者的 24996 个种植体,放疗组的成功率为 86.2%,未放疗组的成功率为 95.2%。根据 AMSTAR 2,只有一项系统评价质量较高。

结论

对于接受过头颈部癌症放疗的患者,口腔种植体的口腔修复是一种有效的治疗方法。然而,考虑到所发现的证据水平,需要进一步进行设计更好的研究,以提高临床决策的可信度。

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1
Effectiveness of dental implants in patients undergoing radiotherapy for head and neck cancer: An umbrella review.头颈部癌症放疗患者中牙种植体的疗效:伞式综述。
Spec Care Dentist. 2024 Jan-Feb;44(1):40-56. doi: 10.1111/scd.12840. Epub 2023 Feb 28.
2
Comment on: Effectiveness of dental implants in patients undergoing radiotherapy for head and neck cancer: An umbrella review (doi: 10.1111/scd.12840).评论:头颈部癌放疗患者牙种植体的有效性:一项伞状综述(doi: 10.1111/scd.12840)
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引用本文的文献

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Survival of dental implants in irradiated head and neck cancer patients compared to non-irradiated patients: An umbrella review.与未接受放疗的患者相比,头颈部癌放疗患者牙种植体的存活率:一项系统综述。
PLoS One. 2025 Sep 3;20(9):e0324388. doi: 10.1371/journal.pone.0324388. eCollection 2025.
2
Implant-Supported Oral Rehabilitation in Head and Neck Cancer Patients: A 20-Year Single-Center Study (2005-2024).头颈部癌症患者的种植体支持式口腔修复:一项为期20年的单中心研究(2005 - 2024年)
J Clin Med. 2025 Aug 1;14(15):5435. doi: 10.3390/jcm14155435.
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The effects of high-dose radiation therapy on bone: a scoping review.
高剂量放射治疗对骨骼的影响:一项范围综述
Radiat Oncol J. 2024 Jun;42(2):95-103. doi: 10.3857/roj.2023.00969. Epub 2024 Feb 27.