辐照对储存在20摄氏度下的人体血小板的影响。

Effects of irradiation on human platelets stored at 20 degrees C.

作者信息

Marin P, Le Forestier C, Beaujean F, Duedari N, Valls A

机构信息

Postgraduate School of Haematology, Farreras Valenti, Hospital Clínico, University of Barcelona, Spain.

出版信息

Radiother Oncol. 1987 Aug;9(4):273-9. doi: 10.1016/s0167-8140(87)80148-2.

DOI:10.1016/s0167-8140(87)80148-2

PMID:3685449

Abstract

The morphologic and functional properties of platelets after irradiation with 2500 rads and storage, in first-generation containers, for 48 h in a liquid phase at 20 degrees C with continuous horizontal agitation have been analyzed and compared with a control group of the same platelets which were not irradiated. The preservation technique induced changes in the morphology and aggregation stimulated by ADP and collagen. However, no significant differences were found between the irradiated and non-irradiated groups. Irradiation is not a conditioning factor to add to the hazards of preserving platelets in a liquid phase.

摘要

对2500拉德辐照后的血小板，在20摄氏度液相中、连续水平搅拌下于第一代容器中储存48小时后的形态学和功能特性进行了分析，并与未辐照的相同血小板对照组进行了比较。这种保存技术引起了由二磷酸腺苷（ADP）和胶原蛋白刺激的形态变化和聚集。然而，辐照组和未辐照组之间未发现显著差异。辐照不是增加液相保存血小板风险的一个制约因素。