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[体外二氧化碳清除的最新研究]

[Recent research on extracorporeal carbon dioxide removal].

作者信息

Wang Xiao-Xin, Guo Yan

机构信息

Neonatal Medical Center, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2023 Feb 15;25(2):205-209. doi: 10.7499/j.issn.1008-8830.2208187.

DOI:10.7499/j.issn.1008-8830.2208187
PMID:36854699
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9979386/
Abstract

Extracorporeal carbon dioxide removal is an artificial lung auxiliary technique based on extrapulmonary gas exchange and can effectively remove carbon dioxide and provide oxygenation to a certain extent, and it is one of the effective treatment techniques for hypercapnia developed after mechanical ventilation and extracorporeal membrane oxygenation in recent years and has wide application prospect. This article elaborates on the development, working principle, advantages, classification, complications, and clinical application of extracorporeal carbon dioxide removal, so as to provide a new choice for extracorporeal carbon dioxide removal in clinical practice.

摘要

体外二氧化碳清除是一种基于肺外气体交换的人工肺辅助技术,能有效清除二氧化碳并在一定程度上提供氧合,是近年来继机械通气和体外膜肺氧合之后发展起来的治疗高碳酸血症的有效治疗技术之一,具有广阔的应用前景。本文阐述了体外二氧化碳清除的发展、工作原理、优点、分类、并发症及临床应用,以期为临床实践中体外二氧化碳清除提供新的选择。

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1
[Recent research on extracorporeal carbon dioxide removal].[体外二氧化碳清除的最新研究]
Zhongguo Dang Dai Er Ke Za Zhi. 2023 Feb 15;25(2):205-209. doi: 10.7499/j.issn.1008-8830.2208187.
2
[Clinical value of the implication of extracorporeal carbon dioxide removal in patients with acute respiratory distress syndrome].[体外二氧化碳清除对急性呼吸窘迫综合征患者的临床价值]
Zhonghua Yi Xue Za Zhi. 2024 Apr 16;104(15):1242-1246. doi: 10.3760/cma.j.cn112137-20231026-00907.
3
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J Extra Corpor Technol. 2017 Jun;49(2):112-114.
4
Update on extracorporeal carbon dioxide removal: a comprehensive review on principles, indications, efficiency, and complications.体外二氧化碳去除技术的最新进展:原理、适应证、效率和并发症的全面综述。
Perfusion. 2020 Sep;35(6):492-508. doi: 10.1177/0267659120906048. Epub 2020 Mar 10.
5
Regional anticoagulation with heparin of an extracorporeal CO removal circuit: a case report.体外二氧化碳清除回路肝素局部抗凝:一例报告
J Med Case Rep. 2019 May 3;13(1):123. doi: 10.1186/s13256-019-2051-6.
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Intraoperative extracorporeal carbon dioxide removal support for minimally invasive surgical treatment of vanishing lung syndrome.微创治疗消失肺综合征术中体外二氧化碳去除支持。
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Intensive Care Med. 2001 Aug;27(8):1340-51. doi: 10.1007/s001340100993.
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Extracorporeal Carbon Dioxide Removal in the Treatment of Status Asthmaticus.体外二氧化碳去除术在哮喘持续状态治疗中的应用。
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The evolving role and practical application of extracorporeal carbon dioxide removal in critical care.体外二氧化碳去除在危重病中的不断演变的作用和实际应用。
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本文引用的文献

1
Basics of Extracorporeal Membrane Oxygenation.体外膜肺氧合基础。
Surg Clin North Am. 2022 Feb;102(1):23-35. doi: 10.1016/j.suc.2021.09.001.
2
Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial.体外二氧化碳去除辅助低潮气量通气与标准通气对急性低氧性呼吸衰竭患者 90 天死亡率的影响:REST 随机临床试验。
JAMA. 2021 Sep 21;326(11):1013-1023. doi: 10.1001/jama.2021.13374.
3
Treatment of Severe Hypercapnic Respiratory Failure Caused by SARS-CoV-2 Lung Injury with ECCOR Using the Hemolung Respiratory Assist System.使用Hemolung呼吸辅助系统的体外二氧化碳移除(ECCOR)治疗由SARS-CoV-2肺损伤引起的严重高碳酸血症性呼吸衰竭
Case Rep Crit Care. 2021 Jun 29;2021:9958343. doi: 10.1155/2021/9958343. eCollection 2021.
4
ECCOR in 12 COVID-19 ARDS Patients With Extremely Low Compliance and Refractory Hypercapnia.12例极低顺应性和难治性高碳酸血症的COVID-19急性呼吸窘迫综合征患者的体外二氧化碳清除(ECCOR)治疗
Front Med (Lausanne). 2021 Jul 8;8:654658. doi: 10.3389/fmed.2021.654658. eCollection 2021.
5
Carbon dioxide levels in neonates: what are safe parameters?新生儿二氧化碳水平:什么是安全参数?
Pediatr Res. 2022 Apr;91(5):1049-1056. doi: 10.1038/s41390-021-01473-y. Epub 2021 Jul 6.
6
Extracorporeal carbon dioxide removal (ECCO2R) in COPD and ARDS patients with severe hypercapnic respiratory failure. A retrospective case-control study.体外二氧化碳去除 (ECCO2R) 在 COPD 和 ARDS 伴严重高碳酸血症呼吸衰竭患者中的应用。一项回顾性病例对照研究。
Turk J Med Sci. 2021 Aug 30;51(4):2127-2135. doi: 10.3906/sag-2012-151.
7
Extracorporeal Carbon Dioxide Removal or Extracorporeal Membrane Oxygenation: Why Should We Care?体外二氧化碳清除或体外膜肺氧合:我们为何要关注?
Crit Care Med. 2021 May 1;49(5):e546-e547. doi: 10.1097/CCM.0000000000004844.
8
Decapneization as supportive therapy for the treatment of status asthmaticus: a case report.脱机作为重症哮喘治疗的支持性疗法:一例病例报告
J Med Case Rep. 2021 Apr 8;15(1):200. doi: 10.1186/s13256-021-02689-6.
9
Physiological Basis of Extracorporeal Membrane Oxygenation and Extracorporeal Carbon Dioxide Removal in Respiratory Failure.呼吸衰竭中体外膜肺氧合及体外二氧化碳清除的生理基础
Membranes (Basel). 2021 Mar 22;11(3):225. doi: 10.3390/membranes11030225.
10
The use of extracorporeal CO removal in acute respiratory failure.体外二氧化碳清除在急性呼吸衰竭中的应用。
Ann Intensive Care. 2021 Mar 11;11(1):43. doi: 10.1186/s13613-021-00824-6.