[精神分裂症患者视觉和听觉诱发电位的地形学特征]

[Topographic aspects of visual and auditory evoked potentials in schizophrenics].

作者信息

Laurian S, Gaillard J M, Oros L, Schöpf J

机构信息

Clinique psychiatrique universitaire de Lausanne, Hôpital de Cery, Prilly, Suisse.

出版信息

Rev Electroencephalogr Neurophysiol Clin. 1987 Sep;17(3):271-7. doi: 10.1016/s0370-4475(87)80064-3.

DOI:10.1016/s0370-4475(87)80064-3

PMID:3685572

Abstract

The EPs to bilaterally presented non-verbal and non-cognitive visual and auditory stimuli were studied in 15 schizophrenics and 15 normal subjects. Many anomalies of exogenous components of VEPs and AEPs were observed in schizophrenics in comparison with control subjects, pointing to an abnormal cerebral functioning. So, the patients presented: (1) a less interhemispheric difference in latency of P100 component of VEPs over the occipital area; (2) a decrease or a lack of left hemispheric predominance of P2 component of AEPs over the central area; (3) a lower interhemispheric waveform similarity both for VEPs and AEPs. These results suggest a lower hemispheric specialization and interhemispheric synchronization of EPs in schizophrenics.

摘要

在15名精神分裂症患者和15名正常受试者中研究了对双侧呈现的非言语、非认知视觉和听觉刺激的事件相关电位（EPs）。与对照受试者相比，在精神分裂症患者中观察到许多视觉诱发电位（VEPs）和听觉诱发电位（AEPs）外源成分的异常，这表明大脑功能异常。因此，这些患者表现出：（1）枕叶区域VEPs的P100成分潜伏期的半球间差异较小；（2）中央区域AEPs的P2成分左半球优势降低或缺乏；（3）VEPs和AEPs的半球间波形相似性较低。这些结果表明精神分裂症患者的EPs半球特化和半球间同步性较低。