Slice2Volume：融合多模态医学成像和光显微镜数据的辐照损伤脑组织的 3D 图像。
Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D.
机构信息
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technical University Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden 01309, Germany; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology - OncoRay, Dresden 01309, Germany; DFG Cluster of Excellence Physics of Life, TU Dresden, Dresden 01307, Germany.
OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technical University Dresden, Helmholtz-Zentrum Dresden-Rossendorf, Dresden 01309, Germany; German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany; Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Barcelona 08028, Spain.
出版信息
Radiother Oncol. 2023 May;182:109591. doi: 10.1016/j.radonc.2023.109591. Epub 2023 Feb 28.
Comprehending cellular changes of radiation-induced brain injury is crucial to prevent and treat the pathology. We provide a unique open dataset of proton-irradiated mouse brains consisting of medical imaging, radiation dose simulations, and large-scale microscopy images, all registered into a common coordinate system. This allows dose-dependent analyses on single-cell level.
理解放射性脑损伤的细胞变化对于预防和治疗病理学至关重要。我们提供了一个独特的质子辐照小鼠大脑开放数据集，其中包括医学成像、辐射剂量模拟和大规模显微镜图像，所有这些都注册到一个共同的坐标系中。这允许在单细胞水平上进行剂量依赖性分析。
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