Broström O, Monsén U, Nordenwall B, Sörstad J, Hellers G
Dept. of Medicine, S:t Eriks Hospital, Stockholm, Sweden.
Scand J Gastroenterol. 1987 Oct;22(8):907-13. doi: 10.3109/00365528708991934.
All 1274 patients in Stockholm County who were diagnosed as having ulcerative colitis during the 25-year period 1955-79 were followed up and studied with regard to prognosis and mortality. There were 109 deaths recorded--41 caused by ulcerative colitis and 68 from other causes. The cumulative survival probability (computed by life-table methods) was worse than expected. For males it was approximately 80% at 20 years, to be compared with the approximately 97% expected in the background population. For females the corresponding figures were approximately 85% and 98%, respectively. The excess death risk increased with increasing age and was more commonly due to unrelated causes than to ulcerative colitis as such. In patients with total colitis at onset the death risk was greater than for other patients during the first years of disease. Thereafter the prognosis was, if anything, better than in other cases. There was no major change in postoperative mortality or general mortality pattern during the 25 years of observation.
对斯德哥尔摩郡在1955年至1979年这25年间被诊断为患有溃疡性结肠炎的所有1274例患者进行了随访，并对其预后和死亡率进行了研究。记录到109例死亡——41例由溃疡性结肠炎导致，68例由其他原因导致。累积生存概率（通过寿命表法计算）低于预期。男性在20岁时约为80%，而背景人群预期约为97%。女性的相应数字分别约为85%和98%。额外死亡风险随年龄增长而增加，更多是由无关原因而非溃疡性结肠炎本身导致。发病时为全结肠炎的患者在疾病最初几年的死亡风险高于其他患者。此后，其预后即便有差异也比其他情况要好。在25年的观察期内，术后死亡率或总体死亡模式没有重大变化。
